Cerebral hypoperfusion

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Cerebral hypoperfusion is inadequate blood flow to the brain.[1][2] Chronic cerebral hypoperfusion is linked to neurocognitive disorders.[2]

Orthostatic cerebral hypoperfusion syndrome[edit | edit source]

Novak (2016) states that orthostatic cerebral hypoperfusion syndrome (OCHOs) is defined by:

  1. abnormal orthostatic drop of cerebral blood flow velocity (CBFv) during the tilt test and
  2. absence of orthostatic hypotension, arrhythmia, vascular abnormalities, or other causes of abnormal orthostatic CBFv[3]

Prevalence[edit | edit source]

A study by Dutch scientists of 429 ME/CFS patients found that 90% of them had an abnormal cerebral blood flow reduction (i.e. cerebral hypoperfusion) during orthostatic stress testing.[4]

Symptom recognition[edit | edit source]

Notable studies[edit | edit source]

Possible causes[edit | edit source]

Orthostatic intolerance

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. ↑ Merrian-Webster Medical Dictionary. "Medical Definition of HYPOPERFUSION". Merrian-Webster Dictionary. Retrieved April 28, 2020.
  2. ↑ 2.0 2.1 Ciacciarelli, Antonio; Sette, Giuliano; Giubilei, Franco; Orzi, Francesco (March 1, 2020). "Chronic cerebral hypoperfusion: An undefined, relevant entity" (PDF). Journal of Clinical Neuroscience. 73: 8–12. doi:10.1016/j.jocn.2020.01.026. ISSN 0967-5868.
  3. ↑ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754393/
  4. ↑ Clmc, van Campen; Fwa, Verheugt; Pc, Rowe; Fc, Visser (February 8, 2020). "Cerebral blood flow is reduced in ME/CFS during head-up tilt testing even in the absence of hypotension or tachycardia: A quantitative, controlled study using Doppler echography". Clinical neurophysiology practice. 5. doi:10.1016/j.cnp.2020.01.003. ISSN 2467-981X. PMC 7044650. PMID 32140630.
  5. ↑ Costa, D.C.; Tannock, C.; Brostoff, J. (November 1995). "Brainstem perfusion is impaired in chronic fatigue syndrome". QJM: monthly journal of the Association of Physicians. 88 (11): 767–773. ISSN 1460-2725. PMID 8542261.
  6. ↑ Miwa, Kunihisa; Inoue, Yukichi (September 2018). "The etiologic relation between disequilibrium and orthostatic intolerance in patients with myalgic encephalomyelitis (chronic fatigue syndrome)". Journal of Cardiology. 72 (3): 261–264. doi:10.1016/j.jjcc.2018.02.010. PMID 29588088.
  7. ↑ "visser van campen cfs cerebral - Search Results - PubMed". PubMed. Retrieved October 10, 2024.

cerebral 1. of or relating to the brain or the intellect 2. of, relating to, affecting, or being the cerebrum.

1. of or relating to the brain or the intellect 2. of, relating to, affecting, or being the cerebrum.[1]}

cerebral 1. of or relating to the brain or the intellect 2. of, relating to, affecting, or being the cerebrum.

(CBF) - the amount of blood that goes through the arterial tree in the brain in a given amount of time[2]

cerebral blood flow (CBF) - the amount of blood that goes through the arterial tree in the brain in a given amount of time

brainstem Region of the midbrain in adults, includes midbrain, pons, and medulla oblongata and develops.

orthostatic intolerance (OI) - The development of symptoms when standing upright, where symptoms are relieved upon reclining. Patients with orthostatic intolerance have trouble remaining upright for more than a few seconds or a few minutes, depending upon severity. In severe orthostatic intolerance, patients may not be able to sit upright in bed. Orthostatic intolerance is often a sign of dysautonomia. There are different types of orthostatic intolerance, including postural orthostatic tachycardia syndrome (POTS).

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