CYP21A2 mutation associated psychiatric spectrum

A group of medical and psychiatric conditions are proposed to be linked to mutations in the cytochrome P450 family 21 subfamily A member (CYP21A2) gene, these have been termed CYP21A2 mutation associated psychiatric spectrum or CAPS by Dr Sharon Megalathery. This hypothesis has not been academically peer reviewed and the term is not in general use.

The gene CYP21A2 is also known as Cytochrome P450 family 21 subfamily A member 2 CYP21A2.

Theory

This theory has been called RCCX Genetic Module Theory and suggest a common genetic link with a broad range of medical and psychiatric illnesses, including:

• ME/CFS
• Chronic Lyme disease
• Fibromyalgia
• hypermobile Ehlers-Danlos Syndrome
• Autism spectrum conditions
• ADHD

RCCX genetic module theory lacks evidence and has not yet been the subject of peer-reviewed clinical research.

Main article: RCCX Genetic Module Theory

See also

• RCCX Genetic Module Theory
• Cytochrome P450 family 21 subfamily A member 2 (CYP21A2)

Learn more

• From RCCX Theory to Stress-Induced Mitochondrial Shutdown *[https://www.rccxandillness.com/rccx-theory-part-ii-connecting-rccx-theory-to-mitochondrial-shutdown.html From RCCX Theory to Stress-Induced Mitochondrial Shutdown