Portal:Myalgic Encephalomyelitis

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Myalgic Encephalomyelitis

Myalgic encephalomyelitis (ME) is a disease of the nervous system and the immune system. Its hallmark symptom is post-exertional malaise, a severe worsening of symptoms after cognitive or physical exertion. Common symptoms of ME include: cognitive dysfunction, orthostatic intolerance, and unrefreshing sleep. Many patients will also have headaches, pain, muscle weakness or muscle fatigability, sensitivities to light, sound, touch, foods, odors, and an array of other symptoms. (more...)


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Post-exertional malaise (PEM) is a worsening of many ME/CFS symptoms as a result of physical or mental exertion. PEM, sometimes called Post-exertional Neuroimmune Exhaustion (PENE), is often regarded as the main symptom that differentiates Myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS) from other fatiguing illnesses. (more...)


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Diagnostic criteria

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If you think you might have ME, read these diagnostic criteria and see how they compare with your symptoms:


Co-morbid diagnoses

Learn more about the diagnoses that are commonly co-morbid with and related to ME. Note: it is possible to both have ME and one of these diagnoses, or to have one of these diagnoses and not have ME.

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graph of common ME symptoms
Myalgic Encephalomyelitis is a complex multi-systemic illness. Common symptoms include neurological symptoms, immune and gastrointestinal symptoms, cardiovascular and endocrine symptoms.

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The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.