Brains of People With Chronic Fatigue Syndrome Offer Clues About Disorder - New York Times: Well (2014)
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Brain imaging studies mentioned in article
- 2014, The Stanford ME/CFS Initiative, directed by Dr. Jose Montoya and working with Dr. Michael Zeineh and colleagues, studied the brains of patients with CFS and healthy people and found distinct differences between the two groups. Radiology researchers have discovered that the brains of patients with CFS have diminished white matter and white matter abnormalities in the right hemisphere.
- 2014, A Japanese PET study looked at neuroinflammation in 9 patients with ME/CFS and 10 controls. They measured a protein expressed by activated microglia, and found that values in the cingulate cortex, hippocampus, amygdala, thalamus, midbrain, and pons were 45%–199% higher in ME/CFS patients than in healthy controls. The values in the amygdala, thalamus, and midbrain positively correlated with cognitive impairment score, the values in the cingulate cortex and thalamus positively correlated with pain score, and the value in the hippocampus positively correlated with depression score.
- Brains of People With Chronic Fatigue Syndrome Offer Clues About Disorder
- Zeineh, Michael M; Kang, James; Atlas, Scott W; et al. (2014-10-29), "Right Arcuate Fasciculus Abnormality in Chronic Fatigue Syndrome", Radiology, 274 (2): 517–526, doi:10.1148/radiol.14141079
- Goldman, Bruce (2014-10-28), "Study finds brain abnormalities in chronic fatigue patients", Stanford Medicine News Center
- Tuller, David (2014-11-24), "Brains of People With Chronic Fatigue Syndrome Offer Clues About Disorder", NY Times
- Nakatomi, Yasuhito; Mizuno, Kei; Ishii, Akira; et al. (2014-03-24), "Neuroinflammation in Patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: An ¹¹C-(R)-PK11195 PET Study", Journal of Nuclear Medicine, 2014 Jun;55(6): 945-50, PMID 24665088, doi:10.2967/jnumed.113.131045