Yasuyoshi Watanabe

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Yasuyoshi Watanabe, MD, PhD, is the Director of RIKEN BDR-DAIKIN Collaboration Center at RIKEN Center for Life Science Technologies, Kobe City, Hyogo, Japan.[1] He is a Professor, Department of Physiology, Osaka City Graduate School of Medicine, Osaka City, Japan, where his specialties are fatigue science and molecular neuroimaging.[2]

Dr. Watanabe serves as an associate editor of the journal Fatigue: Biomedicine, Health & Behavior.[3]

IOM Committee on Diagnostic Criteria for ME/CFS[edit | edit source]

Dr Watanabe was a reviewer for the 2015 report produced by the Institute of Medicine's Committee on Diagnostic Criteria for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.[4]

Book chapter[edit | edit source]

  • 2020, Integrated Imaging on Fatigue and Chronic Fatigue, a chapter in the book, Make Life Visible[5] - (Full chapter)

Notable studies[edit | edit source]

  • 2010, A new hypothesis of chronic fatigue syndrome: Co-conditioning theory[6] - (Abstract)
  • 2013, Neurocognitive impairment in childhood chronic fatigue syndrome[7] - (Full Text)
  • 2014, Neuroinflammation in Patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: An ¹¹C-(R)-PK11195 PET Study[8] - (Full Text)
  • 2015, Less efficient and costly processes of frontal cortex in childhood chronic fatigue syndrome[9] - (Full Text)
  • 2015, Frontier studies on fatigue, autonomic nerve dysfunction, and sleep-rhythm disorder[10] - (Full Text)
  • 2016, Neural effect of physical fatigue on mental fatigue: a magnetoencephalography study[11] - (Abstract)
  • 2016, Roles of the right dorsolateral prefrontal cortex during physical fatigue: a magnetoencephalographic study[2] - (Abstract)
  • 2016, Ubiquinol-10 supplementation improves autonomic nervous function and cognitive function in chronic fatigue syndrome[12] - (Abstract)
  • 2016, Index markers of chronic fatigue syndrome with dysfunction of TCA and urea cycles[13] - (Full Text)
  • 2016, Low putamen activity associated with poor reward sensitivity in childhood chronic fatigue syndrome[14] - (Full text)
  • 2018, History of Researches on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome[15] - (Abstract)
  • 2018, Neuroinflammation in the Brain of Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome[16] - (Abstract)
  • 2018, Brain Science on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome[17] - (Abstract)
  • 2018, Association of Fatigue and Stress With Gray Matter Volume[18] - (Full text)
  • 2019, Decreased alpha-band oscillatory brain activity prior to movement initiated by perception of fatigue sensation[19] - (Full text)

Talks and interviews[edit | edit source]

Online presence[edit | edit source]

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. "Laboratory for Pathophysiological and Health Science | RIKEN". www.riken.jp. Retrieved Oct 31, 2019. 
  2. 2.02.1 Tanaka, Masaaki; Ishii, Akira; Watanabe, Yasuyoshi (Jul 2, 2016). "Roles of the right dorsolateral prefrontal cortex during physical fatigue: a magnetoencephalographic study". Fatigue: Biomedicine, Health & Behavior. 4 (3): 146–157. doi:10.1080/21641846.2016.1175179. ISSN 2164-1846. 
  3. "Fatigue: Biomedicine, Health & Behavior". www.tandfonline.com. Retrieved Oct 31, 2019. 
  4. "Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Redefining an Illness" (PDF). National Academies Press. 2015. Retrieved Oct 31, 2019. 
  5. Watanabe, Yasuyoshi; Tanaka, Masaaki; Ishii, Akira; Mizuno, Kei; Sasaki, Akihiro; Yamano, Emi; Cui, Yilong; Fukuda, Sanae; Kataoka, Yosky (2020). Toyama, Yoshiaki; Miyawaki, Atsushi; Nakamura, Masaya; Jinzaki, Masahiro, eds. "Integrated Imaging on Fatigue and Chronic Fatigue". Make Life Visible. Singapore: Springer Singapore: 227–233. doi:10.1007/978-981-13-7908-6_23. ISBN 9789811379079. 
  6. Tanakaa, Masaaki; Watanabe, Yasuyoshi (Aug 1, 2010). "A new hypothesis of chronic fatigue syndrome: Co-conditioning theory". Medical Hypotheses. 75 (2): 244–249. doi:10.1016/j.mehy.2010.02.032. ISSN 0306-9877. 
  7. Mizuno, Kei; Tanaka, Masaaki; Tanabe, Hiroki C.; Joudoi, Takako; Kawatani, Junko; Shigihara, Yoshihito; Tomoda, Akemi; Miike, Teruhisa; Imai-Matsumura, Kyoko (2015). "Less efficient and costly processes of frontal cortex in childhood chronic fatigue syndrome". NeuroImage: Clinical. 9: 355–368. doi:10.1016/j.nicl.2015.09.001. PMC 4589845Freely accessible. PMID 26594619. 
  8. Nakatomi, Y.; Mizuno, K.; Ishii, A.; Wada, Y.; Tanaka, M.; Tazawa, S.; Onoe, K.; Fukuda, S.; Kawabe, J.; Takahashi, Kazuhiro; Kataoka, Yosky; Shiomi, Susumu; Yamaguti, Kouzi; Masaaki, Inaba; Kuratsune, Hirohiko; Watanabe, Yasuyoshi (Jun 1, 2014). "Neuroinflammation in Patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: An 11C-(R)-PK11195 PET Study". Journal of Nuclear Medicine. 55 (6): 945–950. doi:10.2967/jnumed.113.131045. ISSN 0161-5505. 
  9. Mizuno, Kei; Tanaka, Masaaki; Tanabe, Hiroki C.; Joudoi, Takako; Kawatani, Junko; Shigihara, Yoshihito; Tomoda, Akemi; Miike, Teruhisa; Imai-Matsumura, Kyoko; Sadatod, Norihiro; Watanabe, Yasuyoshi (2015). "Less efficient and costly processes of frontal cortex in childhood chronic fatigue syndrome". NeuroImage: Clinical. 9: 355–368. doi:10.1016/j.nicl.2015.09.001. PMC 4589845Freely accessible. PMID 26594619. 
  10. Tanaka, Masaaki; Tajima, Seiki; Mizuno, Kei; Ishii, Akira; Konishi, Yukuo; Miike, Teruhisa; Watanabe, Yasuyoshi (Nov 2015). "Frontier studies on fatigue, autonomic nerve dysfunction, and sleep-rhythm disorder". The Journal of Physiological Sciences. 65 (6): 483–498. doi:10.1007/s12576-015-0399-y. ISSN 1880-6546. PMC 4621713Freely accessible. PMID 26420687. 
  11. Tanaka, Masaaki; Ishii, Akira; Watanabe, Yasuyoshi (Apr 2, 2016). "Neural effect of physical fatigue on mental fatigue: a magnetoencephalography study". Fatigue: Biomedicine, Health & Behavior. 4 (2): 104–114. doi:10.1080/21641846.2016.1167471. ISSN 2164-1846. 
  12. Fukuda, S; Nojima, J; Kajimoto, O; Yamaguti, K; Nakatomi, Y; Kuratsune, H; Watanabe, Y (Apr 29, 2016), "Ubiquinol-10 supplementation improves autonomic nervous function and cognitive function in chronic fatigue syndrome", BioFactors (Oxford, England), doi:10.1002/biof.1293, PMID 27125909 
  13. Yamano, Emi; Sugimoto, Masahiro; Hirayama, Akiyoshi; Kume, Satoshi; Yamato, Masanori; Jin, Guanghua; Tajima, Seiki; Goda, Nobuhito; Iwai, Kazuhiro; Fukuda, Sanae; Yamaguti, Kouzi; Kuratsune, Hirohiko; Soga, Tomoyoshi; Watanabe, Yasuyoshi; Kataoka, Yosky (2016), "Index markers of chronic fatigue syndrome with dysfunction of TCA and urea cycles", Scientific Reports, 6 (34990), doi:10.1038/srep34990, PMID 27725700 
  14. Mizuno, Kei; Kawatani, Junko; Tajima, Kanako; Sasaki, Akihiro T.; Yoneda, Tetsuya; Komi, Masanori; Hirai, Toshinori; Tomoda, Akemi; Joudoi, Takako; Watanabe, Yasuyoshi (Feb 2016). "Low putamen activity associated with poor reward sensitivity in childhood chronic fatigue syndrome". NeuroImage: Clinical. 12: 600–606. doi:10.1016/j.nicl.2016.09.016. PMC 5043413Freely accessible. PMID 27709065. 
  15. 渡辺, 恭良; 倉恒, 弘彦 (Jan 1, 2018), 特集 筋痛性脳脊髄炎/慢性疲労症候群の今 筋痛性脳脊髄炎/慢性疲労症候群研究の潮流, 株式会社医学書院, doi:10.11477/mf.1416200943, retrieved Oct 31, 2019 
  16. Nakatomi, Y; Kuratsune, H; Watanabe, Y (2018), "Neuroinflammation in the Brain of Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome", Brain Nerve, 70 (1): 19-25, doi:10.11477/mf.1416200945, PMID 29348371 
  17. 渡辺, 恭良 (Nov 1, 2018), 増大特集 脳科学で解き明かす精神神経症候 筋痛性脳脊髄炎/慢性疲労症候群の脳科学研究, 株式会社医学書院, doi:10.11477/mf.1416201164, retrieved Oct 31, 2019 
  18. Kokubun, Keisuke; Nemoto, Kiyotaka; Oka, Hiroki; Fukuda, Hiroki; Yamakawa, Yoshinori; Watanabe, Yasuyoshi (Jul 24, 2018). "Association of Fatigue and Stress With Gray Matter Volume". Frontiers in Behavioral Neuroscience. 12: 154. doi:10.3389/fnbeh.2018.00154. ISSN 1662-5153. PMC 6066525Freely accessible. PMID 30087602. 
  19. Ishii, Akira; Matsuo, Takashi; Nakamura, Chika; Uji, Masato; Yoshikawa, Takahiro; Watanabe, Yasuyoshi (Dec 2019). "Decreased alpha-band oscillatory brain activity prior to movement initiated by perception of fatigue sensation". Scientific Reports. 9 (1): 4000. doi:10.1038/s41598-019-40605-7. ISSN 2045-2322. PMC 6408540Freely accessible. PMID 30850665. 

ME/CFS - An acronym that combines myalgic encephalomyelitis with chronic fatigue syndrome. Sometimes they are combined because people have trouble distinguishing one from the other. Sometimes they are combined because people see them as synonyms of each other.

myalgic encephalomyelitis (ME) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

chronic fatigue syndrome (CFS) - A fatigue-based illness. The term CFS was invented invented by the U.S. Centers for Disease Control as an replacement for myalgic encephalomyelitis (ME). Some view CFS as a neurological disease, others use the term for any unexplained long-term fatigue. Sometimes used as a the term as a synonym of myalgic encephalomyelitis, despite the different diagnostic criteria.

chronic fatigue syndrome (CFS) - A fatigue-based illness. The term CFS was invented invented by the U.S. Centers for Disease Control as an replacement for myalgic encephalomyelitis (ME). Some view CFS as a neurological disease, others use the term for any unexplained long-term fatigue. Sometimes used as a the term as a synonym of myalgic encephalomyelitis, despite the different diagnostic criteria.

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.