MTHFR

MTHFR is short for the enzyme called methylenetetrahydrofolate reductase (methylenetetrahydrofolate reductase) or 10-Methylenetetrahydrofolate Reductase or NADPH or NAD(P)H. Sometimes the term MTHFR is also used when referring to the genes that transcribes methylenetetrahydrofolate reductase.

Function

The enzyme catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, which assists in the production of building blocks for DNA.

See also

• Methylation cycle
• Methylation cycle hypothesis
• Genetic testing
• 23andMe
• Ancestry DNA

Learn more

• MTHFR gene - Gene cards

enzyme a substance produced by a living organism which acts as a catalyst to bring about a specific biochemical reaction.

See myalgic encephalomyelitis.

See chronic fatigue syndrome.