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Macrophagic myofasciitis
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
 | This article is a stub. |
Macrophagic myofasciitis or MMF is a rare condition that causes chronic fatigue and muscle pain, and may result in patients being diagnosed with chronic fatigue syndrome.[1] It is regarded as a form of autoimmune syndrome induced by adjuvants (ASIA).[1]
Signs and symptoms[edit | edit source]
- Widespread muscle pain
- Chronic fatigue
- Cognitive dysfunction (brain fog)
- Weakness at the site of a vaccine
- Raised level of creatine kinase
- Raised level of erythrocyte sedimentation rate[1][2]
Diagnosis[edit | edit source]
A muscle biopsy at the site of the vaccine[1]
Treatment[edit | edit source]
ME/CFS[edit | edit source]
Many patients with MMF meet the now disused Oxford criteria for chronic fatigue syndrome, or the more commonly used Fukuda criteria.
Notable articles[edit | edit source]
- 2003, Chronic fatigue syndrome in patients with macrophagic myofasciitis[3] - (Full text)
- 2006, Atypical presentation of macrophagic myofasciitis 10 years post vaccination[4] - (Full text)
- 2009, A role for the body burden of aluminium in vaccine-associated macrophagic myofasciitis and chronic fatigue syndrome[5] - (Full text)
- 2014, Clinical features in patients with long-lasting macrophagic myofasciitis[6] - (Full text)
See also[edit | edit source]
- Differential diagnosis
- Autoimmune syndrome induced by adjuvants
- Idiopathic chronic fatigue
Learn more[edit | edit source]
References[edit | edit source]
- ↑ Jump up to: 1.0 1.1 1.2 1.3 Gherardi, RK; Authier, FJ (February 1, 2012). "Macrophagic myofasciitis: characterization and pathophysiology". Lupus. 21 (2): 184–189. doi:10.1177/0961203311429557. ISSN 0961-2033. PMC 3623725. PMID 22235051.
- ↑ https://books.google.com/books/about/Textbook_of_Pediatric_Rheumatology_E_Boo.html?id=oEemcpeEufoC
- ↑ Authier, François-Jérôme; Sauvat, Stéphane; Champey, Julien; Drogou, Irène; Coquet, Michèle; Gherardi, Romain K. (2003). "Chronic fatigue syndrome in patients with macrophagic myofasciitis". Arthritis & Rheumatism. 48 (2): 569–570. doi:10.1002/art.10740. ISSN 1529-0131.
- ↑ Ryan, Aisling M.; Bermingham, Niamh; Harrington, Hugh J.; Keohane, Catherine (December 2006). "Atypical presentation of macrophagic myofasciitis 10 years post vaccination". Neuromuscular Disorders. 16 (12): 867–869. doi:10.1016/j.nmd.2006.07.017. ISSN 0960-8966.
- ↑ Exley, Christopher; Swarbrick, Louise; Gherardi, Rhomain K.; Authier, Francois-Jérôme (February 1, 2009). "A role for the body burden of aluminium in vaccine-associated macrophagic myofasciitis and chronic fatigue syndrome". Medical Hypotheses. 72 (2): 135–139. doi:10.1016/j.mehy.2008.09.040. ISSN 0306-9877.
- ↑ Rigolet, Muriel; Aouizerate, Jessie; Couette, Maryline; Ragunathan-Thangarajah, Nilusha; Aoun-Sebaiti, Mehdi; Gherardi, Romain Kroum; Cadusseau, Josette; Authier, François Jérôme (2014). "Clinical Features in Patients with Long-Lasting Macrophagic Myofasciitis". Frontiers in Neurology. 5. doi:10.3389/fneur.2014.00230. ISSN 1664-2295.
