Karen Schlauch

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Karen Schlauch, PhD, is a mathematician in the Molecular Biosciences department of the University of Nevada, Reno, US.[1] She has worked on the genetics of chronic fatigue syndrome.

Education[edit | edit source]

  • 1989, B.S., Mathematics/Computer Science, University of Illinois[1]
  • 1991, M.A., Mathematics, Eastern Illinois University[1]
  • 1994, M.S., Mathematics, New Mexico State University[1]
  • 1998, Ph.D., Mathematics, New Mexico State University[1]

Research[edit | edit source]

Schlauch develops mathematical and statistical techniques to use in analysis of large and complex whole-Omics experiments for biological hypotheses.[1] Collaborating physicians, she has worked to predict possible associations of genotype and disease in conditions including pre-term labor, Chronic Fatigue Syndrome, Gulf War Syndrome, Alzheimer's disease and obesity.[1]

Schlauch is the lead statistical geneticist on the Healthy Nevada Project housed at the Desert Research Institute and Renown Hospital.[1]

Publications[edit | edit source]

  • 2016, Genome-wide association analysis identifies genetic variations in subjects with myalgic encephalomyelitis/chronic fatigue syndrome[2] (Full text)

References[edit | edit source]

  1. 1.01.11.21.31.41.51.61.7 "Karen Schlauch". www.unr.edu. Retrieved Jul 27, 2019. 
  2. Schlauch, Karen A.; Khaiboullina, Svetlana F.; De Meirleir, Kenny L.; Rawat, Shanti; Petereit, J; Rizvanov, Albert A; Blatt, Nataliya; Mijatovic, Tatjana; Kulick, D; Palotás, András; Lombardi, Vincent C. (2016), "Genome-wide association analysis identifies genetic variations in subjects with myalgic encephalomyelitis/chronic fatigue syndrome", Translational Psychiatry, 6 (2): e730, doi:10.1038/tp.2015.208 

genome - an organism’s complete set of DNA, including all of its genes

myalgic encephalomyelitis (ME) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

chronic fatigue syndrome (CFS) - A controversial term, invented by the U.S. Centers for Disease Control, that generally refers to a collection of symptoms as “fatigue”. There have been multiple attempts to come up with a set of diagnostic criteria to define this term, but few of those diagnostic criteria are currently in use. Previous attempts to define this term include the Fukuda criteria and the Oxford criteria. Some view the term as a useful diagnostic category for people with long-term fatigue of unexplained origin. Others view the term as a derogatory term borne out of animus towards patients. Some view the term as a synonym of myalgic encephalomyelitis, while others view myalgic encephalomyelitis as a distinct disease.

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.