IP-10 is Interferon gamma (INF-γ) inducible protein 10. It is a chemokine, and important for recruiting natural killer cells to the myocardium, and for limiting viral duplication in murine (mice/rodent) coxsackievirus infection.
Alternative names[edit | edit source]
IP-10 is also known as:
- C-X-C motif chemokine 10
- IFN-γ inducible protein 10
- Interferon gamma inducible protein 10
- 10 kDa interferon-gamma induced protein
Notable studies[edit | edit source]
- This study found "compelling evidence" of the role of several cytokines/chemokine]]s in the physiological and cognitive pathology in a group of patients with chronic fatigue syndrome, although these patients were selected using the Oxford criteria, which includes many patients with chronic fatigue not caused by ME/CFS.
Learn more[edit | edit source]
See also[edit | edit source]
References[edit | edit source]
- "CXCL10 - C-X-C motif chemokine 10 precursor - Homo sapiens (Human) - CXCL10 gene & protein". www.uniprot.org. Retrieved Jan 24, 2019.
- Loux, Tara J.; Lotze, Michael T.; Zeh, Herbert J. (Jan 1, 2010). Lotze, Michael T.; Thomson, Angus W., eds. "Chapter Fourteen - NK cells as recipients of cytokine signals". San Diego: Academic Press: 189–201. ISBN 9780123704542.
- Lee, James J.; Rosenberg, Helene F., eds. (Jan 1, 2013). "Chapter 6 - Eosinophil Trafficking". Eosinophils in Health and Disease. Boston: Academic Press: 121–166. ISBN 9780123943859.
- McArdle, Anne; Gusnanto, Arief; Earl, Kate; Sakellariou, George; Lawton, Clare; Owens, Daniel; Close, Graeme; Beadsworth, Michael; Dye, Louise (Apr 1, 2017). "The role of IP-10 in Chronic Fatigue Syndrome". The FASEB Journal. 1 (1_supplement): lb789. doi:10.1096/fasebj.31.1_supplement.lb789.
chronic fatigue syndrome (CFS) - A fatigue-based illness. The term CFS was invented invented by the U.S. Centers for Disease Control as an replacement for myalgic encephalomyelitis (ME). Some view CFS as a neurological disease, others use the term for any unexplained long-term fatigue. Sometimes used as a the term as a synonym of myalgic encephalomyelitis, despite the different diagnostic criteria.