Glucose

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Glucose is a simple sugar.

ME/CFS[edit | edit source]

A study of skeletal muscle cell cultures from 10 subjects with CFS found blunted glucose uptake after electrical stimulation.[1]

A study of cerebral glucose metabolism in 26 patients with chronic fatigue syndrome via 18-fluorodeoxyglucose positron emission tomography (FDG-PET) found abnormalities in approximately half of patients.[2] A 1998 PET study also found evidence of reduced metabolism in 18 patients.[3]

References[edit | edit source]

  1. Newton, Julia L.; Walker, Mark; Jones, David E.; Brown, Audrey E. (April 2, 2015). "Abnormalities of AMPK Activation and Glucose Uptake in Cultured Skeletal Muscle Cells from Individuals with Chronic Fatigue Syndrome". PLOS ONE. 10 (4): e0122982. doi:10.1371/journal.pone.0122982. ISSN 1932-6203. PMC 4383615. PMID 25836975.
  2. Bartenstein, P.; Egle, U.T.; Schreckenberger, M.; Hardt, J.; Nix, W.A.; Siessmeier, T. (July 1, 2003). "Observer independent analysis of cerebral glucose metabolism in patients with chronic fatigue syndrome". Journal of Neurology, Neurosurgery & Psychiatry. 74 (7): 922–928. doi:10.1136/jnnp.74.7.922. ISSN 0022-3050. PMID 12810781.
  3. Tirelli, Umberto; Chierichetti, Franca; Tavio, Marcello; Simonelli, Cecilia; Bianchin, Gianluigi; Zanco, Pierluigi; Ferlin, Giorgio (September 28, 1998). "Brain positron emission tomography (PET) in chronic fatigue syndrome: preliminary data". The American Journal of Medicine. 105 (3, Supplement 1): 54S–58S. doi:10.1016/S0002-9343(98)00179-X. ISSN 0002-9343.