Gamma-aminobutyric acid type B receptor subunit 1
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Gamma-Aminobutyric Acid Type B Receptor Subunit 1 or GABBR1 is a protein encoding gene that has neurotransmitter effects.[1]
Alternative names[edit | edit source]
- GPRC3A
- GABA B Receptor, 1[1]
Function[edit | edit source]
GABBR1 encodes a receptor for GABA (gamma-aminobutyric acid), which is the main inhibitory neurotransmitter in the central nervous system of humans.[1]
Diseases[edit | edit source]
Defects in this gene may be linked to:
- Epilepsy
- Schizophrenia
Other diseases that may be associated with GABBR1 include:
- Temporal Lobe Epilepsy
- Childhood Absence Epilepsy[2]
Drugs[edit | edit source]
- Baclofenac targets GABBR1 and GABBR2.[2]
ME/CFS[edit | edit source]
See also[edit | edit source]
- GABA - related neurotransmitter
Learn more[edit | edit source]
References[edit | edit source]
- ↑ 1.0 1.1 1.2 "Gamma-Aminobutyric Acid Type B Receptor Subunit 1". genecards.org. Retrieved November 9, 2021.
- ↑ 2.0 2.1 Sriram, Krishna; Insel, Paul A. (April 2018). "G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?" (PDF). Molecular Pharmacology. 93 (4): 251–258. doi:10.1124/mol.117.111062. ISSN 1521-0111. PMC 5820538. PMID 29298813.
