Gamma-aminobutyric acid type B receptor subunit 1

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Gamma-Aminobutyric Acid Type B Receptor Subunit 1 or GABBR1 is a protein encoding gene that has neurotransmitter effects.[1]

Alternative names[edit | edit source]

  • GPRC3A
  • GABA B Receptor, 1[1]

Function[edit | edit source]

GABBR1 encodes a receptor for GABA (gamma-aminobutyric acid), which is the main inhibitory neurotransmitter in the central nervous system of humans.[1]

Diseases[edit | edit source]

Defects in this gene may be linked to:

  • Epilepsy
  • Schizophrenia

Other diseases that may be associated with GABBR1 include:

  • Temporal Lobe Epilepsy
  • Childhood Absence Epilepsy[2]

Drugs[edit | edit source]

ME/CFS[edit | edit source]

See also[edit | edit source]

  • GABA - related neurotransmitter

Learn more[edit | edit source]

References[edit | edit source]

  1. 1.0 1.1 1.2 "Gamma-Aminobutyric Acid Type B Receptor Subunit 1". Retrieved November 9, 2021.
  2. 2.0 2.1 Sriram, Krishna; Insel, Paul A. (April 2018). "G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?" (PDF). Molecular Pharmacology. 93 (4): 251–258. doi:10.1124/mol.117.111062. ISSN 1521-0111. PMC 5820538. PMID 29298813.