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Four-symptom criteria
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
The Four-symptom criteria, also known as the Four-item empiric criteria, is a definition of ME/CFS proposed by Leonard A. Jason.
Definition[edit | edit source]
Patients must fulfill all four criteria:
- Post-exertional malaise
- Fatigue
- Unrefreshing sleep
- A neurocognitive symptom[1]
Studies[edit | edit source]
- 2016, Chronic Fatigue Syndrome versus Systemic Exertion Intolerance Disease
- 2015, Chronic fatigue syndrome and myalgic encephalomyelitis: towards an empirical case definition
