An echovirus (previously written ECHO, or enteric cytopathic human orphan) is a type of enterovirus. There are several different serotypes of echovirus known to infect humans.
In the United States, ARUP Laboratories and Cambridge Biomedical offer a serum microneutralization assay that is designed to measure the concentration of serum antibodies to five serotypes of the virus; 6, 7, 9, 11, and 30. This specific assay has been shown to be sensitive for detection of chronic infections in ME patients. A persistent fourfold or greater rise in antibody titer is often found in these patients, which is not often found in healthy controls.
A complement fixation assay for echovirus serotypes is available in the United States from LabCorp and Quest Diagnostics, however this specific type of assay has not been found to be sensitive for the chronic infections found in ME patients.
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References[edit | edit source]
- "AN OUTBREAK OF DISEASE BELIEVED TO HAVE BEEN CAUSED BY ECHO 9 VIRUS". Annals of Internal Medicine. 51 (2): 248. Aug 1, 1959. doi:10.7326/0003-4819-51-2-248. ISSN 0003-4819.
serum - the clear yellowish fluid that remains from blood plasma after clotting factors have been removed by clot formation
assay - 1. (verb) analysis (as of an ore or drug) to determine the presence, absence, or quantity of one or more components. 2. (noun) In biochemistry, any laboratory protocol used to test a sample for one or more qualities.