D-Ribose

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Ribose is a carbohydrate with the formula C5H10O5, that exists in two forms: D-ribose, which occurs in nature and L-ribose, which is the mirror image of D-ribose and does not occur in nature.[1]

D-ribose is a building block used by the cells in one of the chemical pathways that makes the energy molecule, ATP.[2]

D-ribose comes in powder form, tastes sweet, and can used as a sugar substitute in drinks or on cereal.

Use in ME/CFS and FM[edit | edit source]

It is used as a supplement for help boost muscle energy, such as for athletes and people with ME/CFS, Fibromyalgia, and coronary artery disease.[3] The theory is that if one supplies the body with the precursors to ATP, then it will be easier for the body to make ATP.[2]

Sources[edit | edit source]

Supplemental d-ribose is manufactured from corn, so is to be avoided by those with corn allergies or insensitivities.[2]

Evidence[edit | edit source]

A small study of 41 patients by Jacob Teitelbaum resulted in: "Approximately 66% of patients experienced significant improvement while on D-ribose [at a dose of 5 g, three times a day], with an average increase in energy on the VAS [visual analog scale categories: energy; sleep; mental clarity; and pain intensity] of 45% and an average improvement in overall well-being of 30% (p < 0.0001)." The study authors concluded that "D-ribose significantly reduced clinical symptoms in patients suffering from fibromyalgia and chronic fatigue syndrome".[4]

Learn more[edit | edit source]

See also[edit | edit source]

Muscle fatigability

References[edit | edit source]

  1. Wikipedia - Ribose
  2. 2.02.12.2 Doctor Myhill - D-ribose
  3. WebMD - Vitamins and Supplements - Ribose
  4. Teitelbaum, Jacob E.; Johnson, Clarence; St Cyr, John (November 2006), "The use of D-ribose in chronic fatigue syndrome and fibromyalgia: a pilot study", Journal of Alternative and Complementary Medicine (New York, N.Y.), 12 (9): 857–862, doi:10.1089/acm.2006.12.857, ISSN 1075-5535, PMID 17109576 

ME/CFS - An acronym that combines myalgic encephalomyelitis with chronic fatigue syndrome. Sometimes they are combined because people have trouble distinguishing one from the other. Sometimes they are combined because people see them as synonyms of each other.

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.