Complexin 2

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Complexin 2 or CPLX2 or CPX-2 or Synaphin 1 is a protein-encoding gene.[1]

Function[edit | edit source]

CPLX2 is associated with a number of diseases including schizophrenia and familial temporal lobe 7 epilepsy.[1]

ME/CFS[edit | edit source]

The ME/CFS Gene Study is still collecting data, but the pilot study publication by Perez et al. (2019) found that CPLX2 was one of the ten relatively common genes or gene variants that were both significantly more common in people with ME/CFS, and likely to be harmful.[2]

Notable studies[edit | edit source]

  • 2019, Genetic Predisposition for Immune System, Hormone, and Metabolic Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Pilot Study[2] (Full text)

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]