Chlamydia pneumoniae

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Chlamydia pneumoniae (also referred to as Chlamydophila pneumoniae or CPN) is an intracellular bacterium of the species Chlamydophila, and can infect people via airborne transmission. It is a major cause of community-acquired pneumonia.[1] It has been implicated as a potential cause of ME/CFS in a subset of patients. A study by Chia & Chia found that 10% of their patients had a chlamydophila pneumoniae infection which may have caused or contributed to their ME/CFS.[2]

A chronic chlamydophila pneumoniae infection can be treated with antibiotics.[3]

Testing[edit | edit source]

Accurately testing for chlamydia pneumoniae can be difficult, therefore, a negative blood test may not mean you do not have an infection. Additionally, there is a general shortage worldwide of facilities which can identify/diagnose Chlamydia pneumoniae.[4] Common tests for chlamydophila pneumoniae include the microimmunofluorescence (MIF) test[5] or via biopsy.

Dr. John Chia notes that most ME/CFS patients with active Chlamydia pneumoniae infection will have high IgG antibody levels (but IgM is negative). Dr. Chia has treated patients with titers as low as 1:128.[6]

Treatment[edit | edit source]

A chlamydophila pneumoniae infection, while an uncommon cause of ME/CFS, is one of the more treatable forms. Antibiotic treatment with azithromycin or rifampin can therefore improve or even cure patients. Chia & Chia found that while antibiotic treatment was successful in many patients, relapse was also common.[2] Some patients have reported recovery after being treated with Dr Stratton's original protocol[7]. More information on treatment options can be found on CPN Help's Treatment Protocols page[8].

Notable studies[edit | edit source]

  • 1999, Chronic Chlamydia pneumoniae Infection: A Treatable Cause of Chronic Fatigue Syndrome[2] - (Article)
  • 2003, Multiple co-infections (Mycoplasma, Chlamydia, human herpes virus-6) in blood of chronic fatigue syndrome patients: association with signs and symptoms[9] - (Abstract)

Learn more[edit | edit source]

References[edit | edit source]

antibodies Antibody/immunoglobulin refers to any of a large number of specific proteins produced by B cells that act against an antigen in an immune response.

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.