Corticotropin-releasing factor receptor type 2
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Corticotropin-releasing factor receptor type 2 or corticotropin-releasing hormone receptor 2 or CRFR2 or CRHR2 or CRF2 or CRF2 or CRH2 is a protein but CRFR2 may also refer to the gene that encodes the protein.[1]
ME/CFS[edit | edit source]
CRFR2 may be upregulated in ME/CFS patients - although this has not yet been proven - and the degree of upregulation may be linked to the severity of ME/CFS.[2] The new drug CT38 is currently in clinical trials at the Bateman Horne Center to determine if downregulating CRFR2 is an effective treatment or cure for ME/CFS.
Notable studies[edit | edit source]
- 2021, Acute Corticotropin-Releasing Factor Receptor Type 2 Agonism Results in Sustained Symptom Improvement in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome[3] (Full text)
See also[edit | edit source]
Learn more[edit | edit source]
- Sep 2021, Cortene Weighs-In on Future Plans for CT38 - Bateman Horne Center
- Sep 2021, Cortene study published
- Sep 2021, Dr Bateman on Cortene and CT38
References[edit | edit source]
- ↑ "CRHR2 corticotropin releasing hormone receptor 2 [Homo sapiens (human)] - Gene - NCBI". ncbi.nlm.nih.gov. Retrieved November 20, 2021.
- ↑ Linford, Angela (September 3, 2021). "Futue Plans for CT38". Bateman Horne Center. Retrieved November 20, 2021.
- ↑ Pereira, Gerard; Gillies, Hunter; Chanda, Sanjay; Corbett, Michael; Vernon, Suzanne D.; Milani, Tina; Bateman, Lucinda (2021). "Acute Corticotropin-Releasing Factor Receptor Type 2 Agonism Results in Sustained Symptom Improvement in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". Frontiers in Systems Neuroscience. 15: 84. doi:10.3389/fnsys.2021.698240. ISSN 1662-5137. PMC 8441022. PMID 34539356.
