Björn Sigurdsson

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Björn Sigurdsson, Dr. med., (1913 -1959) was the founder and first director of the Institute for Experimental Pathology at Keldur, University of Iceland, Reykjavík, Iceland. He introduced the concept of slow viral infections (lentiviruses), that is, viruses that have a slow progression to disease after primary infection. While working with the contagious sheep diseases, maedi and visna, he and his collaborators were the first to grow a lentivirus in vitro.[1]

Sigurdsson studied and wrote about the outbreak of Akureyri disease, the name given to a disease epidemic simulating poliomyelitis. In a study of Icelandic children vaccinated against polio in 1956, Sigurdsson, et. al found significant differences in antibody response to vaccination depending on where the children lived. Children in Egilsstadir had only a slight antibody rise to type 2 and type 3 poliovirus, while children in Thorshofn, which had recently had an outbreak of epidemic myalgic encephalomyelitis, had a much stronger antibody response response to the polio vaccine. Sigurdsson postulated that this might be explained by "the existence of basic immunity acquired through a related infection."[2]


Notable studies[edit | edit source]

  • 1950, A disease epidemic in Iceland simulating poliomyelitis[3] - (Abstract)
  • 1956, Clinical findings six years after outbreak of Akureyri disease[4] - (Abstract)
  • 1958, Response to poliomyelitis vaccination[2]


See also[edit | edit source]

Learn more[edit | edit source]

  • Wikipedia
  • Institution

References[edit | edit source]

  1. Ingvarsson, Sigurdur (Jan 2013). "In memoriam Björn Sigurdsson born 100 years ago (editorial)". Icelandic Agricultural Sciences. Retrieved Jun 20, 2019. 
  2. 2.02.1 Sigurdsson, B (Feb 15, 1958). "Response to poliomyelitis vaccination". The Lancet. 1: 370–1. 
  3. Sigurdsson, B (Sep 1950). "A disease epidemic in Iceland simulating poliomyelitis". American Journal of Hygiene. 52: 222–38. 
  4. Sigurdsson, B. (May 26, 1956). "Clinical findings six years after outbreak of Akureyri disease". Lancet (London, England). 270 (6926): 766–767. ISSN 0140-6736. PMID 13320872. 

Antibody - Antibodies or immunoglobulin refers to any of a large number of specific proteins produced by B cells that act against an antigen in an immune response.

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