From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

BRRF1 encodes the transcription factor for Na, which is may have a role in Epstein-Barr virus (EBV)replication.[1][2][3]

Function[edit | edit source]

ME/CFS[edit | edit source]

Ariza (2021) published a hypothesis | last4 showing a role for BRRF1 and BLLF3 in the immune dysfunction found in ME/CFS.

Notable[edit | edit source]

  • 2021, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: The Human Herpesviruses Are Back![1] - (Full text)

See also[edit | edit source]

Learn more[edit | edit source]

  • Outside articles: e.g. WebMD, Merck Manual

References[edit | edit source]

  1. 1.0 1.1 Ariza, Maria Eugenia (January 29, 2021). "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: The Human Herpesviruses Are Back!". Biomolecules. 11 (2): 185. doi:10.3390/biom11020185. ISSN 2218-273X. PMC 7912523. PMID 33572802.
  2. Hong, Gregory K.; Delecluse, Henri-Jacques; Gruffat, Henri; Morrison, Thomas E.; Feng, Wen-Hai; Sergeant, Alain; Kenney, Shannon C. (May 2004). "The BRRF1 Early Gene of Epstein-Barr Virus Encodes a Transcription Factor That Enhances Induction of Lytic Infection by BRLF1". Journal of Virology. 78 (10): 4983–4992. doi:10.1128/JVI.78.10.4983-4992.2004. ISSN 0022-538X. PMID 15113878.
  3. Yoshida, Masahiro; Watanabe, Takahiro; Narita, Yohei; Sato, Yoshitaka; Goshima, Fumi; Kimura, Hiroshi; Murata, Takayuki (July 20, 2017). "The Epstein-Barr Virus BRRF1 Gene Is Dispensable for Viral Replication in HEK293 cells and Transformation". Scientific Reports. 7 (1): 6044. doi:10.1038/s41598-017-06413-7. ISSN 2045-2322.