Angiotensin-converting enzyme

Angiotensin-converting enzyme or ACE is a non-specific enzyme involved in metabolizing many different peptides, and converts angiotensin I to angiotensin II (ACE2).

ACE drugs

ACE inhibitors

Angiotensin-converting enzyme inhibitors increase the level of ACE2. ACE inhibitors are one of several classes of drugs recommended for the initial treatment of hypertension, and are mainly used for high blood pressure and heart failure.

ACE inhibitors include:

• Captopril, a sulfur containing inhibitor
• Benazepril (Lotensiin)
• Cilazapril (Inhibace)
• Enalapril (Vasotec, Epaned)
• Fosinopril, a phosphorus containing inhibitor
• Lisinopril (Prinivil, Zestril)
• Moexipril (Univasc)
• Perindopril (Aceon)
• Quinapril (Accupril)
• Ramipril (Altace)
• Spirapril (Espirapril, Renormax)
• Trandolapril (Mavik)
• Zofenopril

Recently, concerns have been expressed about the effect of ACE inhibitors in patients exposed to the SARS-CoV-2 virus which causes COVID-19 or the SARS-CoV virus that causes SARS.

See also

• Angiotensin I converting enzyme II (ACE2)

Learn more

• Angiotensin-converting enzyme inhibitors - drugbank.ca

enzyme a substance produced by a living organism which acts as a catalyst to bring about a specific biochemical reaction.

See myalgic encephalomyelitis.

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