1958 Athens outbreak
1958 Athens outbreak: In June 1958 an unusual neurological disease spread through the Queen Frederica School for Midwives, which is attached to the Alexandra Maternity Hospital, Athens, Greece. All twenty-seven cases reported occurred in females. Twenty-five were graduates or student midwives of the school, one was a female servant of the outpatient medical clinic, and one was a nurse of a neighboring hospital who visited the hospital laboratory every day she was on duty. No doctors or patients exposed to the nurses prior to the manifestation of the illness became ill. The outbreak was viewed as an episode of benign myalgic encephalomyelitis.
The cerebrospinal fluid examined by lumbar puncture was normal in 3 out of the 4 patients tested.
See also[edit | edit source]
References[edit | edit source]
- Daikos, GK; Garzonis, S; Paleologue, A; Bousvaros, GA; Papadoyannakis, N (1959), "Benign myalgic encephalomyelitis. An outbreak in a Nurse's School in Athens.", Lancet, 273 (7075): 693-696, doi:10.1016/S0140-6736(59)91883-5
- McEvedy, Colin; Beard, A. W. (1970), "Concept of Benign Myalgic Encephalomyelitis", British Medical Journal, 1970 (1): 11-15, PMID 5411596
Myalgic encephalomyelitis (ME) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.