Talk:Fibromyalgia

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Blood test[edit source | reply | new]

It would be helpful for the blood test section to be expanded, the article has a PDF published under CC-BY-4.0 license so these images (even the whole PDF) can be copied and added to ME-pedia. notjusttired (talk) 08:38, 25 March 2019 (EDT)

This is research. It is not an established blood test. Put it on the Fibromyalgia notable studies page. A blood test is being developed to diagnose fibromyalgia; a study by Hacksaw et al (2018) looked for a fibromyalgia biomarker and found a unique metabolic fingerprint which distinguished all patients with fibromyalgia from those with systemic lupus erythematosus, rheumatoid arthritis and osteoarthritis.[1] The study only analysed blood samples from rheumatic diseases, so it did not include patients with ME/CFS or other illnesses which can chronic pain.[1]--76.18.68.198 11:39, 25 March 2019 (EDT)

Very large study - source for graphs?[edit source | reply | new]

This study of over 3,000 people with Fibromyalgia would be a great source for graphs of symptom prevalence or other interesting factors, the Graph tool can draw them quickly. Frequent symptoms or types of pain could also be good info for tables. notjusttired (talk) 18:02, 16 April 2019 (EDT)

2010, A cross-sectional survey of 3035 patients with fibromyalgia: subgroups of patients with typical comorbidities and sensory symptom profiles[2] (Full text)

Notable studies[edit source | reply | new]

This is a list of Notable news stories about the studies so would be best being teenaged, a list of Notable studies would be useful. notjusttired (talk) 08:38, 25 March 2019 (EDT)

Notable studies has its own page. Fibromyalgia notable studies. There had to be a page created because the Fibromyalgia page was too long and could not be edited using View Editing.--76.18.68.198 11:39, 25 March 2019 (EDT)
I created and populated most of the Fibromyalgia pages. If you add, please add the information to the correct areas and pages.--76.18.68.198 11:39, 25 March 2019 (EDT)

-- ~Njt (talk) 23:39, March 22, 2021 (UTC)[edit source | reply | new]

Differences from Depression[edit source | reply | new]

There seems a lack of info on websites about this, I thought it might be helpful to cover, including pointing out that a significant proportion with fibromyalgia do not have depression (or other mental health disorders).

Sources

  • 2008, The relationship between fibromyalgia and major depressive disorder: a comprehensive review[4] (Abstract)
  • 2010, Anxiety and depressive symptoms in fibromyalgia are related to poor perception of health but not to pain sensitivity or cerebral processing of pain[5] (Abstract)

~Njt (talk) 23:39, March 22, 2021 (UTC) Amended/expanded ~Njt (talk) 00:26, March 26, 2021 (UTC)

Notable studies to add[edit source | reply | new]

  • 2007, Clinical and Economic Characteristics of Patients With Fibromyalgia Syndrome[12] (Abstract)
  • 2010, Pain Inhibition Is Deficient in Chronic Widespread Pain but Normal in Major Depressive Disorder[14] (Abstract)
  • 2011, Improving the Recognition and Diagnosis of Fibromyalgia[15] (Full text)
  • ADDED 2011, Fibromyalgia and neuropathic pain - differences and similarities. A comparison of 3057 patients with diabetic painful neuropathy and fibromyalgia[16] (Full text)
  • 2011, The Clinical Concept of Fibromyalgia as a Changing Paradigm in the Past 20 Years[17] (Full text)
  • 2011, The comparative burden of mild, moderate and severe Fibromyalgia: results from a cross-sectional survey in the United States[18] (Full text)
  • 2017, Diagnostic confounders of chronic widespread pain: not always fibromyalgia[19] (Full text)
  • 2019, A systematic review and meta-analysis of the prevalence of small fiber pathology in fibromyalgia: Implications for a new paradigm in fibromyalgia etiopathogenesis[20] (Abstract)

Differences from ME/CFS[edit source | reply | new]

(suggestion) ~Njt (talk) 23:39, March 22, 2021 (UTC)

Insulin resistance - paper retracted -- ~Njt (talk) 01:15, March 27, 2021 (UTC)[edit source | reply | new]

Moving this content here in case there are new studies supporting this. See Fibromyalgia notable studies or link to papee for retraction notice. ~Njt (talk) 01:15, March 27, 2021 (UTC)

Insulin resistance research[edit source | reply | new]

Age-normalized data was found to show a relationship between insulin resistance/pre-diabetes and Fibromyalgia. In a preliminary study, Fibromyalgia patients were treated with metformin, a common medication for diabetes, and showed a large improvement in myofascial pain.
  1. ↑ 1.0 1.1 Rodriguez-Saona, Luis; Giusti, M. Mónica; Buffington, Charles A. T.; Yu, Lianbo; Madiai, Francesca; Pujolras, Marcal Plans; Sigurdson, Gregory T.; Aykas, Didem P.; Hackshaw, Kevin V. (December 6, 2018). "Metabolic fingerprinting for diagnosis of fibromyalgia and other rheumatologic disorders". Journal of Biological Chemistry: jbc.RA118.005816. doi:10.1074/jbc.RA118.005816. ISSN 0021-9258. PMID 30523152.
  2. ↑ Baron, Ralf; Tölle, Thomas R.; Freynhagen, Rainer; Brosz, Mathias; Gockel, Ulrich; Koroschetz, Jana; Rehm, Stefanie E. (June 1, 2010). "A cross-sectional survey of 3035 patients with fibromyalgia: subgroups of patients with typical comorbidities and sensory symptom profiles". Rheumatology. 49 (6): 1146–1152. doi:10.1093/rheumatology/keq066. ISSN 1462-0324.
  3. ↑ Müller, W.; Schneider, E.M.; Stratz, T. (September 1, 2007). "The classification of fibromyalgia syndrome". Rheumatology International. 27 (11): 1005–1010. doi:10.1007/s00296-007-0403-9. ISSN 1437-160X.
  4. ↑ Pae, Chi-Un; Luyten, Patrick; Marks, David M.; Han, Changsu; Park, Sung-Hwan; Patkar, Ashwin A.; Masand, Prakash S.; Van Houdenhove, Boudewijn (August 1, 2008). "The relationship between fibromyalgia and major depressive disorder: a comprehensive review". Current Medical Research and Opinion. 24 (8): 2359–2371. doi:10.1185/03007990802288338. ISSN 0300-7995. PMID 18606054.
  5. ↑ Jensen, Karin B.; Petzke, Frank; Carville, Serena; Fransson, Peter; Marcus, Hanke; Williams, Steven C.R.; Choy, Ernest; Mainguy, Yves; Gracely, Richard (2010). "Anxiety and depressive symptoms in fibromyalgia are related to poor perception of health but not to pain sensitivity or cerebral processing of pain". Arthritis & Rheumatism. 62 (11): 3488–3495. doi:10.1002/art.27649. ISSN 1529-0131.
  6. ↑ Ablin, Jacob N.; Buskila, Dan; Van Houdenhove, Boudewijn; Luyten, Patrick; Atzeni, Fabiola; Sarzi-Puttini, Piercarlo (June 2012). "Is fibromyalgia a discrete entity?". Autoimmunity Reviews. 11 (8): 585–588. doi:10.1016/j.autrev.2011.10.018. ISSN 1568-9972.
  7. ↑ DeNoon, Daniel J. "Fibromyalgia Isn't Depression". WebMD. Retrieved March 25, 2021.
  8. ↑ World Health Organization (2016). "M79 Other soft tissue disorders, not elsewhere classified". ICD-10 Version:2016. Retrieved March 25, 2021.
  9. ↑ "2021 ICD-10-CM Diagnosis Code M79.7 | Fibromyalgia". ICD10 Data. Retrieved March 25, 2021.
  10. ↑ World Health Organization. "MG30.01 Chronic Widespread Pain". ICD-11 Mortality and Morbidity Statistics. Retrieved December 18, 2018.
  11. ↑ American Psychiatric Association (2013). Diagnostic and Statistical Manual of Mental Disorders (DSM-5®) (5th revision ed.). Washington, D.C.: American Psychiatric Pub. ISBN 9780890425572.
  12. ↑ Lachaine, Jean; Beauchemin, Catherine; Landry, Pierre-Alexandre (May 2010). "Clinical and Economic Characteristics of Patients With Fibromyalgia Syndrome". The Clinical Journal of Pain. 26 (4): 284–290. doi:10.1097/AJP.0b013e3181cf599f. ISSN 0749-8047.
  13. ↑ Rutledge, Dana N.; Mouttapa, Michele; Wood, Patrick B. (September 2009). "Symptom Clusters in Fibromyalgia". Nursing Research. 58 (5): 359–367. doi:10.1097/NNR.0b013e3181b499d2. ISSN 0029-6562.
  14. ↑ Normand, Edith; Potvin, Stéphane; Gaumond, Isabelle; Cloutier, Guylaine; Corbin, Jean-François; Marchand, Serge (August 10, 2010). "Pain Inhibition Is Deficient in Chronic Widespread Pain but Normal in Major Depressive Disorder". The Journal of Clinical Psychiatry. 72 (2): 219–224. doi:10.4088/JCP.08m04969blu. PMID 20816025.
  15. ↑ Arnold, Lesley M.; Clauw, Daniel J.; McCarberg, Bill H. (May 1, 2011). "Improving the Recognition and Diagnosis of Fibromyalgia". Mayo Clinic Proceedings. 86 (5): 457–464. doi:10.4065/mcp.2010.0738. ISSN 0025-6196.
  16. ↑ Koroschetz, Jana; Rehm, Stefanie E.; Gockel, Ulrich; Brosz, Mathias; Freynhagen, Rainer; Tölle, Thomas R.; Baron, Ralf (May 25, 2011). "Fibromyalgia and neuropathic pain - differences and similarities. A comparison of 3057 patients with diabetic painful neuropathy and fibromyalgia". BMC Neurology. 11 (1): 55. doi:10.1186/1471-2377-11-55. ISSN 1471-2377. PMC 3125308. PMID 21612589.
  17. ↑ Fitzcharles, Mary-Ann; Yunus, Muhammad B. (October 29, 2012). "The Clinical Concept of Fibromyalgia as a Changing Paradigm in the Past 20 Years". Pain Research and Treatment. 2012: 1–8. doi:10.1155/2012/184835. ISSN 2090-1542. PMC 3205680. PMID 22135738.
  18. ↑ Schaefer, Caroline; Chandran, Arthi; Hufstader, Meghan; Baik, Rebecca; McNett, Michael; Goldenberg, Don; Gerwin, Robert; Zlateva, Gergana (August 22, 2011). "The comparative burden of mild, moderate and severe Fibromyalgia: results from a cross-sectional survey in the United States". Health and Quality of Life Outcomes. 9 (1): 71. doi:10.1186/1477-7525-9-71. ISSN 1477-7525. PMC 3179696. PMID 21859448.
  19. ↑ Häuser, Winfried; Perrot, Serge; Sommer, Claudia; Shir, Yoram; Fitzcharles, Mary-Ann (May 2017). "Diagnostic confounders of chronic widespread pain: not always fibromyalgia". Pain Reports. 2 (3): e598. doi:10.1097/PR9.0000000000000598. ISSN 2471-2531. PMC 5741304. PMID 29392213.
  20. ↑ "A systematic review and meta-analysis of the prevalence of small fiber pathology in fibromyalgia: Implications for a new paradigm in fibromyalgia etiopathogenesis". Seminars in Arthritis and Rheumatism. 48 (5): 933–940. April 1, 2019. doi:10.1016/j.semarthrit.2018.08.003. ISSN 0049-0172.
  21. ↑ Pappolla, Miguel A.; Manchikanti, Laxmaiah; Andersen, Clark R.; Greig, Nigel H.; Ahmed, Fawad; Fang, Xiang; Seffinger, Michael A.; Trescot, Andrea M. (May 6, 2019). "Is insulin resistance the cause of fibromyalgia? A preliminary report". PLOS ONE. 14 (5): e0216079. doi:10.1371/journal.pone.0216079. ISSN 1932-6203. PMC 6502334. PMID 31059525.

1. of or relating to the brain or the intellect 2. of, relating to, affecting, or being the cerebrum.[1]}

cerebral 1. of or relating to the brain or the intellect 2. of, relating to, affecting, or being the cerebrum.

International Classification of Diseases (ICD) - A system of medical diagnostic codes, created by the World Health Organization (WHO), to classify diseases and other health related conditions for the purpose of international diagnostic consistency. By having common diagnostic codes around the world, health researchers are better able to quantify and track disease burdens. The most current version is called ICD-11. (Learn more: www.who.int)

International Classification of Diseases (ICD) - A system of medical diagnostic codes, created by the World Health Organization (WHO), to classify diseases and other health related conditions for the purpose of international diagnostic consistency. By having common diagnostic codes around the world, health researchers are better able to quantify and track disease burdens. The most current version is called ICD-11. (Learn more: www.who.int)

See Diagnostic and Statistical Manual of Mental Disorders.

Diagnostic and Statistical Manual of Mental Disorders (DSM) - A psychiatric reference book published by the American Psychiatric Association, often referred to as "the psychiatrist's Bible". Although the most recent version (DSM-5) purports to be the authoritative guide to the diagnosis of mental disorders, the editors of both previous versions of the manual have heavily criticized the current version due to the climate of secrecy that shrouded the development of the latest version. 69% of the people who worked on DSM-5 reported having ties to the pharmaceutical industry. Dr. Allen Frances, who headed the development of the previous version, warned of dangerous unintended consequences such as new false 'epidemics'. The British Psychological Society criticized DSM-5 diagnoses as "clearly based largely on social norms, with 'symptoms' that all rely on subjective judgements" and expressed a major concern that "clients and the general public are negatively affected by the continued and continuous medicalisation of their natural and normal responses to their experiences". A petition signed by over 13,000 mental health professionals stated that the lowered diagnostic thresholds in DSM-5, combined with entirely subjective criteria based on western social norms, would "lead to inappropriate medical treatment of vulnerable populations". The director of the US National Institute of Mental Health, Dr. Thomas R. Insel, pointed out that the diagnoses in DSM-5 had no scientific validity whatsoever. (Learn more: www.scientificamerican.com)

International Classification of Diseases (ICD) - A system of medical diagnostic codes, created by the World Health Organization (WHO), to classify diseases and other health related conditions for the purpose of international diagnostic consistency. By having common diagnostic codes around the world, health researchers are better able to quantify and track disease burdens. The most current version is called ICD-11. (Learn more: www.who.int)

(APA) - The main professional organization of psychiatrists and trainee psychiatrists in the United States, and the largest psychiatric organization in the world.[2] Not to be confused with the American Psychological Association (also APA).

American Psychiatric Association (APA) - The main professional organization of psychiatrists and trainee psychiatrists in the United States, and the largest psychiatric organization in the world. Not to be confused with the American Psychological Association (also APA).

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