Carmen Scheibenbogen: Difference between revisions
Notjusttired (talk | contribs) m (Text replacement - "language=En|" to "language=en|") |
(added study and ref) |
||
Line 30: | Line 30: | ||
* 2020, Systematic Review of the Epidemiological Burden of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Across Europe: Current Evidence and EUROMENE Research Recommendations for Epidemiology <ref name="Estevez-Lopez2020">{{Cite journal|last=Estévez-López|first=Fernando|author-link=Fernando Estévez-López|last2=Mudie|first2=Kathleen|author-link2=|last3=Wang-Steverding|first3=Xia|author-link3=Xia Wang-Steverding|last4=Bakken|first4=Inger Johanne|author-link4=Inger Johanne Bakken|last5=Ivanovs|first5=Andrejs|author-link5=|last6=Castro-Marrero|first6=Jesús|author-link6=Jesús Castro-Marrero|last7=Nacul|first7=Luis|author-link7=Luis Nacul|last8=Alegre|first8=Jose|author-link8=José Alegre|last9=Zalewski|first9=Paweł|last10=Słomko|first10=Joanna|author-link10=|last11=Bolle Strand|first11=Elin|author-link11=Elin Bolle Strand|last12=Pheby|first12=Derek|author-link12=Derek Pheby|last13=Shikova|first13=Evelina|author-link13=Evelina Shikova|last14=Lorusso|first14=Lorenzo|author-link14=Lorenzo Lorusso|last15=Capelli|first15=Enrica|author-link15=Enrica Capelli|last16=Sekulic|first16=Slobodan|author-link16=Slobodan Sekulic|last17=Scheibenbogen|first17=Carmen|author-link17=Carmen Scheibenbogen|last18=Sepúlveda|first18=Nuno|author-link18=Nuno Sepúlveda|last19=Murovska|first19=Modra|author-link19=Modra Murovska|last20=Lacerda|first20=Eliana|author-link20=Eliana Lacerda|date=May 2020|title=Systematic Review of the Epidemiological Burden of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Across Europe: Current Evidence and EUROMENE Research Recommendations for Epidemiology|url=https://www.mdpi.com/2077-0383/9/5/1557|journal=Journal of Clinical Medicine|language=en|volume=9|issue=5|pages=1557|doi=10.3390/jcm9051557|pmc=|pmid=|quote=|access-date=|via=}}</ref> - [https://www.mdpi.com/2077-0383/9/5/1557/htm (Full text)] | * 2020, Systematic Review of the Epidemiological Burden of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Across Europe: Current Evidence and EUROMENE Research Recommendations for Epidemiology <ref name="Estevez-Lopez2020">{{Cite journal|last=Estévez-López|first=Fernando|author-link=Fernando Estévez-López|last2=Mudie|first2=Kathleen|author-link2=|last3=Wang-Steverding|first3=Xia|author-link3=Xia Wang-Steverding|last4=Bakken|first4=Inger Johanne|author-link4=Inger Johanne Bakken|last5=Ivanovs|first5=Andrejs|author-link5=|last6=Castro-Marrero|first6=Jesús|author-link6=Jesús Castro-Marrero|last7=Nacul|first7=Luis|author-link7=Luis Nacul|last8=Alegre|first8=Jose|author-link8=José Alegre|last9=Zalewski|first9=Paweł|last10=Słomko|first10=Joanna|author-link10=|last11=Bolle Strand|first11=Elin|author-link11=Elin Bolle Strand|last12=Pheby|first12=Derek|author-link12=Derek Pheby|last13=Shikova|first13=Evelina|author-link13=Evelina Shikova|last14=Lorusso|first14=Lorenzo|author-link14=Lorenzo Lorusso|last15=Capelli|first15=Enrica|author-link15=Enrica Capelli|last16=Sekulic|first16=Slobodan|author-link16=Slobodan Sekulic|last17=Scheibenbogen|first17=Carmen|author-link17=Carmen Scheibenbogen|last18=Sepúlveda|first18=Nuno|author-link18=Nuno Sepúlveda|last19=Murovska|first19=Modra|author-link19=Modra Murovska|last20=Lacerda|first20=Eliana|author-link20=Eliana Lacerda|date=May 2020|title=Systematic Review of the Epidemiological Burden of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Across Europe: Current Evidence and EUROMENE Research Recommendations for Epidemiology|url=https://www.mdpi.com/2077-0383/9/5/1557|journal=Journal of Clinical Medicine|language=en|volume=9|issue=5|pages=1557|doi=10.3390/jcm9051557|pmc=|pmid=|quote=|access-date=|via=}}</ref> - [https://www.mdpi.com/2077-0383/9/5/1557/htm (Full text)] | ||
* 2020, Peripheral endothelial dysfunction in myalgic encephalomyelitis/chronic fatigue syndrome<ref name=endothelial2020>{{Cite journal|last=Scherbakov|first=Nadja|author-link=|last2=Szklarski|first2=Marvin|author-link2=|last3=Hartwig|first3=Jelka|author-link3=|last4=Sotzny|first4=Franziska|author-link4=Franziska Sotzny|last5=Lorenz|first5=Sebastian|author-link5=|last6=Meyer|first6=Antje|author-link6=Antje Meyer|last7=Grabowski|first7=Patricia|last8=Doehner|first8=Wolfram|last9=Scheibenbogen|first9=Carmen|author-link9=Carmen Scheibenbogen|date=2020|title=Peripheral endothelial dysfunction in myalgic encephalomyelitis/chronic fatigue syndrome|url=https://onlinelibrary.wiley.com/doi/abs/10.1002/ehf2.12633|journal=ESC Heart Failure|language=en|volume=7|issue=3|pages=1064–1071|doi=10.1002/ehf2.12633|issn=2055-5822|pmc = 7261521|pmid=32154656|access-date=|quote=|via=}}</ref> - [https://onlinelibrary.wiley.com/doi/abs/10.1002/ehf2.12633 (Full text)] | * 2020, Peripheral endothelial dysfunction in myalgic encephalomyelitis/chronic fatigue syndrome<ref name=endothelial2020>{{Cite journal|last=Scherbakov|first=Nadja|author-link=|last2=Szklarski|first2=Marvin|author-link2=|last3=Hartwig|first3=Jelka|author-link3=|last4=Sotzny|first4=Franziska|author-link4=Franziska Sotzny|last5=Lorenz|first5=Sebastian|author-link5=|last6=Meyer|first6=Antje|author-link6=Antje Meyer|last7=Grabowski|first7=Patricia|last8=Doehner|first8=Wolfram|last9=Scheibenbogen|first9=Carmen|author-link9=Carmen Scheibenbogen|date=2020|title=Peripheral endothelial dysfunction in myalgic encephalomyelitis/chronic fatigue syndrome|url=https://onlinelibrary.wiley.com/doi/abs/10.1002/ehf2.12633|journal=ESC Heart Failure|language=en|volume=7|issue=3|pages=1064–1071|doi=10.1002/ehf2.12633|issn=2055-5822|pmc = 7261521|pmid=32154656|access-date=|quote=|via=}}</ref> - [https://onlinelibrary.wiley.com/doi/abs/10.1002/ehf2.12633 (Full text)] | ||
* 2021, The SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: analysis of high-throughput epigenetic and gene expression studies<ref>{{Cite journal|last=Malato|first=João|author-link=|last2=Sotzny|first2=Franziska|author-link2=Franziska Sotzny|last3=Bauer|first3=Sandra|author-link3=|last4=Freitag|first4=Helma|author-link4=|last5=Fonseca|first5=André|author-link5=|last6=Grabowska|first6=Anna D|author-link6=|last7=Graça|first7=Luís|last8=Cordeiro|first8=Clara|last9=Nacul|first9=Luís|author-link9=Luis Nacul|last10=Lacerda|first10=Eliana M|author-link10= Eliana Lacerda|last11=Castro-Marrero|first11=Jesus|author-link11=Jesus Castro-Marrero|last12=Scheibenbogen|first12=Carmen|author-link12=Carmen Scheibenbogen|last13=Westermeier|first13=Francisco|author-link13=|last14=Sepúlveda|first14=Nuno|author-link14=Nuno Sepúlveda|date=2021-03-24|title=The SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: analysis of high-throughput epigenetic and gene expression studies|url=http://medrxiv.org/lookup/doi/10.1101/2021.03.23.21254175|journal=medRxiv|language=en|volume=|issue=|pages=|doi=10.1101/2021.03.23.21254175|pmc=|pmid=33791744|access-date=|quote=|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010776/ (Full text)] | |||
==Clinic location== | ==Clinic location== |
Revision as of 19:27, June 1, 2021
Professor Doctor Carmen Scheibenbogen is an Internal Medicine physician, ME/CFS doctor and the Professor for Immunology and Deputy Chair, Institute of Medical Immunology, at the University Hospital Charité in Berlin, Germany. Her research focuses on the role of Epstein-Barr virus (EBV), particularly the characterization of EBV specific B cell and T cell response and the enhanced antibody response against EBV peptides in myalgic encephalomyelitis (ME) versus healthy controls.[1]
EUROMENE[edit | edit source]
Professor Scheibenbogen is the Leader of the Biomarkers Working Group of EUROMENE, a European Union, COST Action CA15111, not-for-profit research organization committed to tackling the cause and treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.[2]
Diagnostic test[edit | edit source]
Professor Scheibenbogen helped create the CellTrend Diagnostic Test which may help identify a subset of 20-30% of all patients with ME/CFS. These patients have elevated levels of three auto-antibodies, i.e., against the b2-adrenergic receptor, against the muscarinic cholinergic receptor 3 (M3) and against the muscarinic cholinergic receptor 4 (M4).[3]
Awards[edit | edit source]
- 2016 Ramsay Award Program grant recipient, sponsored by the Solve ME/CFS Initiative for Autoimmune Signature in myalgic encephalomyelitis/chronic fatigue syndrome. This grant was shared with Madlen Löbel, Charité Universitätsmedizin Berlin.[4]
- 2017 Ramsay Award Program grant was awarded to a team comprised of Dr. Carmen Scheibenbogen and Dr. Franziska Sotzny of Charité Universitätsmedizin Berlin, sponsored by the Solve ME/CFS Initiative for researching immunometabolism of T cells and monocytes in ME/CFS.[5]
Notable studies[edit | edit source]
- 2014, Deficient EBV-Specific B- and T-Cell Response in Patients with Chronic Fatigue Syndrome[6] - (Full Text)
- 2015, Frequent IgG subclass and mannose binding lectin deficiency in patients with chronic fatigue syndrome[7] - (Full Text)
- 2015, Polymorphism in COMT is associated with IgG3 subclass level and susceptibility to infection in patients with chronic fatigue syndrome[8] - (Full Text)
- 2016, Antibodies to β adrenergic and muscarinic cholinergic receptors in patients with Chronic Fatigue Syndrome[9] - (Full Text)
- 2017, Serological profiling of the EBV immune response in Chronic Fatigue Syndrome using a peptide microarray[10] -(Full Text)
- 2017, The European ME/CFS Biomarker Landscape project: an initiative of the European network EUROMENE[11] - (Full Text)
- 2018, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome – Evidence for an autoimmune disease[12] - (Full Text)
- 2018, Immunoadsorption to remove ß2 adrenergic receptor antibodies in Chronic Fatigue Syndrome CFS/ME[13] - (Full Text)
- 2018, The expression signature of very long non-coding RNA in myalgic encephalomyelitis/chronic fatigue syndrome[14] - (Full Text)
- 2018, Prevalence and incidence of myalgic encephalomyelitis/chronic fatigue syndrome in Europe—the Euro-epiME study from the European network EUROMENE: a protocol for a systematic review[15] - (Full text)
- 2018, Chronic viral infections in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)[16] - (Full text)
- 2020, IgG stimulated β2 adrenergic receptor activation is attenuated in patients with ME/CFS[17] - (Full text)
- 2020, Human Herpesvirus-6 Reactivation, Mitochondrial Fragmentation, and the Coordination of Antiviral and Metabolic Phenotypes in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome[18] - (Full text)
- 2020, Systematic Review of the Epidemiological Burden of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Across Europe: Current Evidence and EUROMENE Research Recommendations for Epidemiology [19] - (Full text)
- 2020, Peripheral endothelial dysfunction in myalgic encephalomyelitis/chronic fatigue syndrome[20] - (Full text)
- 2021, The SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: analysis of high-throughput epigenetic and gene expression studies[21] - (Full text)
Clinic location[edit | edit source]
- Charité University Medicine, Berlin, Germany
Talks and interviews[edit | edit source]
- 2018, Talk "Chronic Fatigue Syndrome" for General Practitioners
- 2014, Speaker at the 9th Invest in ME International ME Conference DVD available
Online presence[edit | edit source]
See also[edit | edit source]
Learn more[edit | edit source]
References[edit | edit source]
- ↑ "Invest in ME Research - International ME Conferences and Colloquiums Home Page". investinme.org. Retrieved November 14, 2019.
- ↑ "Action CA15111". COST. Retrieved November 14, 2019.
- ↑ "POTS - CFS/ME - CRPS". CellTrend Luckenwalde. Retrieved February 18, 2020.
- ↑ "2016 Ramsay Award Program Results". Solve ME/CFS Initiative. Retrieved November 14, 2019.
- ↑ "2017 Ramsay Award Program Results". Solve ME/CFS Initiative. Retrieved November 14, 2019.
- ↑ Loebel, Madlen; Strohschein, Kristin; Giannini, Carolin; Koelsch, Uwe; Bauer, Sandra; Doebis, Cornelia; Thomas, Sybill; Unterwalder, Nadine; von Baehr, Volker; Reinke, Petra; Knops, Michael; Hanitsch, Leif G.; Meisel, Christian; Volk, Hans-Dieter; Scheibenbogen, Carmen (January 15, 2014), "Deficient EBV-Specific B- and T-Cell Response in Patients with Chronic Fatigue Syndrome", PLoS One, doi:10.1371/journal.pone.0085387
- ↑ Guenther, Sabrina; Loebel, Madlen; Mooslechner, Agnes A; Knops, Michael; Hanitsch, Leif G; Grabowski, Patricia; Wittke, Kirsten; Meisel, Christian; Unterwalder, Nadine; Volk, Hans-Dieter; Scheibenbogen, Carmen (2015), "Frequent IgG subclass and mannose binding lectin deficiency in patients with chronic fatigue syndrome", Human Immunology, 76 (10): 729-35, doi:10.1016/j.humimm.2015.09.028
- ↑ Loebel, Madlen; Mooslechner, Agnes Anna; Bauer, Sandra; Günther, Sabrina; Letsch, Anne; Hanitsch, Leif G; Grabowski, Patricia; Meisel, Christian; Volk, Hans-Dieter; Scheibenbogen, Carmen (2015), "Polymorphism in COMT is associated with IgG3 subclass level and susceptibility to infection in patients with chronic fatigue syndrome", Journal of Translational Medicine, 13, doi:10.1186/s12967-015-0628-4
- ↑ Loebel, M; Grabowski, P; Heidecke, H; Bauer, S; Hanitsch, LG; Wittke, K; Meisel, C; Reinke, P; Volk, H; Fluge, Ø; Mella, O; Scheibenbogen, C (2016), "Antibodies to β adrenergic and muscarinic cholinergic receptors in patients with Chronic Fatigue Syndrome", Brain, behavior, and immunity, 52: 32-39, doi:10.1016/j.bbi.2015.09.013
- ↑ Loebel, Madlen; Eckey, Maren; Sotzny, Franziska; Hahn, Elisabeth; Bauer, Sandra; Grabowski, Patricia; Zerweck, Johannes; Holenya, Pavlo; Hanitsch, Leif G.; Wittke, Kirsten; Borchmann, Peter; Rüffer, Jens-Ulrich; Hiepe, Falk; Ruprecht, Klemens; Behrends, Uta; Meindl, Carola; Volk, Hans-Dieter; Reimer, Ulf; Scheibenbogen, Carmen (2017), "Serological profiling of the EBV immune response in Chronic Fatigue Syndrome using a peptide microarray", PLOS ONE, 12 (6): e0179124, doi:10.1371/journal.pone.0179124
- ↑ Scheibenbogen, Carmen; Freitag, Helma; Blanco, Julià; Capelli, Enrica; Lacerda, Eliana; Authier, Jerome; Meeus, Mira; Castro Marrero, Jesus; Nora-Krukle, Zaiga; Oltra, Elisa; Strand, Elin Bolle; Shikova, Evelina; Sekulic, Slobodan; Murovska, Modra (July 26, 2017). "The European ME/CFS Biomarker Landscape project: an initiative of the European network EUROMENE". Journal of Translational Medicine. 15 (1). doi:10.1186/s12967-017-1263-z. ISSN 1479-5876. PMC 5530475. PMID 28747192.
- ↑ Sotzny, Franziska; Blanco, Julià; Capelli, Enrica; Castro-Marrero, Jesús; Steiner, Sophie; Murovska, Modra; Scheibenbogen, Carmen (2018), "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome – Evidence for an autoimmune disease", Autoimmunity Reviews, doi:10.1016/j.autrev.2018.01.009
- ↑ Scheibenbogen, Carmen; Loebel, Madlen; Freitag, Helma; Krueger, Anne; Bauer, Sandra; Antelmann, Michaela; Doehner, Wolfram; Scherbakov, Nadja; Heidecke, Harald; Reinke, Petra; Volk, Hans-Dieter; Grabowski, Patricia (2018). "Immunoadsorption to remove ß2 adrenergic receptor antibodies in Chronic Fatigue Syndrome CFS/ME". PLoS ONE. 13 (3): e0193672. doi:10.1371/journal.pone.0193672.
- ↑ Yang, Chin-An; Bauer, Sandra; Ho, Yu-Chen; Sotzny, Franziska; Chang, Jan-Gowth; Scheibenbogen, Carmen (August 17, 2018). "The expression signature of very long non-coding RNA in myalgic encephalomyelitis/chronic fatigue syndrome". Journal of Translational Medicine. 16 (1). doi:10.1186/s12967-018-1600-x. ISSN 1479-5876.
- ↑ Estévez-López, Fernando; Castro-Marrero, Jesus; Wang, Xia; Bakken, Inger Johanne; Ivanovs, Andrejs; Nacul, Luis; Sepúlveda, Nuno; Strand, Elin B.; Pheby, Derek; Alegre, José; Scheibenbogen, Carmen; Shikova, Evelina; Lorusso, Lorenzo; Capelli, Enrica; Sekulic, Slobodan; Lacerda, Eliana; Murovska, Modra (September 1, 2018). "Prevalence and incidence of myalgic encephalomyelitis/chronic fatigue syndrome in Europe—the Euro-epiME study from the European network EUROMENE: a protocol for a systematic review". BMJ Open. 8 (9): e020817. doi:10.1136/bmjopen-2017-020817. ISSN 2044-6055. PMID 30181183.
- ↑ Rasa, Santa; Nora-Krukle, Zaiga; Henning, Nina; Eliassen, Eva; Shikova, Evelina; Harrer, Thomas; Scheibenbogen, Carmen; Murovska, Modra; Prusty, Bhupesh K.; European Network on ME/CFS (EUROMENE) (October 1, 2018). "Chronic viral infections in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)". Journal of Translational Medicine. 16 (1). doi:10.1186/s12967-018-1644-y. ISSN 1479-5876. PMID 30285773.
- ↑ Hartwig, Jelka; Sotzny, Franziska; Bauer, Sandra; Heidecke, Harald; Riemekasten, Gabriela; Dragun, Duska; Meisel, Christian; Dames, Claudia; Grabowski, Patricia (March 1, 2020). "IgG stimulated β2 adrenergic receptor activation is attenuated in patients with ME/CFS". Brain, Behavior, & Immunity - Health. 3: 100047. doi:10.1016/j.bbih.2020.100047. ISSN 2666-3546.
- ↑ Schreiner, Philipp; Harrer, Thomas; Scheibenbogen, Carmen; Lamer, Stephanie; Schlosser, Andreas; Naviaux, Robert K.; Prusty, Bhupesh K. (April 1, 2020). "Human Herpesvirus-6 Reactivation, Mitochondrial Fragmentation, and the Coordination of Antiviral and Metabolic Phenotypes in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". ImmunoHorizons. 4 (4): 201–215. doi:10.4049/immunohorizons.2000006. ISSN 2573-7732. PMID 32327453.
- ↑ Estévez-López, Fernando; Mudie, Kathleen; Wang-Steverding, Xia; Bakken, Inger Johanne; Ivanovs, Andrejs; Castro-Marrero, Jesús; Nacul, Luis; Alegre, Jose; Zalewski, Paweł; Słomko, Joanna; Bolle Strand, Elin; Pheby, Derek; Shikova, Evelina; Lorusso, Lorenzo; Capelli, Enrica; Sekulic, Slobodan; Scheibenbogen, Carmen; Sepúlveda, Nuno; Murovska, Modra; Lacerda, Eliana (May 2020). "Systematic Review of the Epidemiological Burden of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Across Europe: Current Evidence and EUROMENE Research Recommendations for Epidemiology". Journal of Clinical Medicine. 9 (5): 1557. doi:10.3390/jcm9051557.
- ↑ Scherbakov, Nadja; Szklarski, Marvin; Hartwig, Jelka; Sotzny, Franziska; Lorenz, Sebastian; Meyer, Antje; Grabowski, Patricia; Doehner, Wolfram; Scheibenbogen, Carmen (2020). "Peripheral endothelial dysfunction in myalgic encephalomyelitis/chronic fatigue syndrome". ESC Heart Failure. 7 (3): 1064–1071. doi:10.1002/ehf2.12633. ISSN 2055-5822. PMC 7261521. PMID 32154656.
- ↑ Malato, João; Sotzny, Franziska; Bauer, Sandra; Freitag, Helma; Fonseca, André; Grabowska, Anna D; Graça, Luís; Cordeiro, Clara; Nacul, Luís; Lacerda, Eliana M; Castro-Marrero, Jesus; Scheibenbogen, Carmen; Westermeier, Francisco; Sepúlveda, Nuno (March 24, 2021). "The SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: analysis of high-throughput epigenetic and gene expression studies". medRxiv. doi:10.1101/2021.03.23.21254175. PMID 33791744.