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Nausea is a sensation of unease and discomfort in the upper stomach with an involuntary urge to vomit.[1] It may precede vomiting, but a person can have nausea without vomiting. When prolonged, it is a debilitating symptom.[2]

Nausea is a relatively common symptom experienced by patients with ME/CFS. It can range from mild to severe and can be relapsing or constant.

Prevalence[edit | edit source]

Katrina Berne reports a prevalence of 60-90% for nausea (as well as a wider prevalence of 50-90% for IBS symptoms including diarrhea, nausea, gas, and abdominal pain).[3]

Symptom recognition[edit | edit source]

Although nausea is not listed as a symptom necessary for diagnosis in any of the current case definitions, it is frequently listed as a secondary symptom in information for patients and physicians.[4][5]

Notable studies[edit | edit source]

Possible causes[edit | edit source]

Possible causes of nausea in ME/CFS patients include orthostatic intolerance,[6] gut inflammation,[7] and slower gastric motility.[8]

Severe nausea may be caused by the digestive motility disorder, gastroparesis, that can be a co-morbid condition with ME/CFS.

Gastroparesis is a neuro-muscular abnormality that causes delayed gastric emptying which, in turn, causes a premature full feeling while eating, bloating, nausea, acid reflux, regurgitation, belching, and occasional vomiting.[8]

Nausea may be caused by a comorbidity such as celiac disease or non-celiac gluten sensitivity (gluten intolerance).

Potential treatments[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. Metz, A; Hebbard, G (Sep 2007), "Nausea and vomiting in adults--a diagnostic approach", Aust Fam Physician, 36 (9): 668–692, PMID 17885699 
  2. "Nausea: Check Your Symptoms and Signs". MedicineNet. Retrieved May 8, 2019. 
  3. Berne, Katrina (Dec 1, 1995), Running on Empty: The Complete Guide to Chronic Fatigue Syndrome (CFIDS), 2nd ed., Hunter House, p. 58, ISBN 978-0897931915 
  4. "Think You Might Have Chronic Fatigue Syndrome? Here are The Symptoms". WebMD. Retrieved May 8, 2019. 
  7. Lakhan, S. E., & Kirchgessner, A. (2010). Gut inflammation in chronic fatigue syndrome. Nutrition & Metabolism, 7, 79.
  8. 8.08.1

ME/CFS - An acronym that combines myalgic encephalomyelitis with chronic fatigue syndrome. Sometimes they are combined because people have trouble distinguishing one from the other. Sometimes they are combined because people see them as synonyms of each other.

α - Greek letter alpha or alfa (symbol)

chronic fatigue syndrome (CFS) - A fatigue-based illness. The term CFS was invented invented by the U.S. Centers for Disease Control as an replacement for myalgic encephalomyelitis (ME). Some view CFS as a neurological disease, others use the term for any unexplained long-term fatigue (idiopathic chronic fatigue) without additional symptoms. Sometimes used as a the term as a synonym of myalgic encephalomyelitis, despite the different diagnostic criteria.

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.