Sophora flavescens

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Sophora flavescens (common name: shrubby sophora) is a plant in the genus Sophora, a genus of the Fabaceae family, that contains about 52 species, nineteen varieties, and seven forms that are widely distributed in Asia, Oceanica, and the Pacific islands. About fifteen species in this genus have a long history of use in Traditional Chinese Medicine. Sophora flavescens root is known as Ku Shen in traditional Chinese medicine. Compounds in Sophora flavescens possessing medicinal properties include oxymatrine, matrine and sophoridine.

Sophora flavescens is the primary component of Equilibrant, an oxymatrine-based product used for treating ME/CFS.

Immunomodulatory properties[edit | edit source]

Antiviral properties[edit | edit source]

Antimicrobial properties[edit | edit source]

It is active against staphylococcus aureus infection.[1][2][3]

Theory[edit | edit source]

Evidence[edit | edit source]

Clinicians[edit | edit source]

Risks and safety[edit | edit source]

Costs and availability[edit | edit source]

Equilibrant[edit | edit source]

Sophora flavescens is the main ingredient in equilibrant, a supplement developed for patients with ME/CFS.

See also[edit | edit source]

References[edit | edit source]

  1. Chen, Li; Cheng, Xiaofang; Shi, Wenyuan; Lu, Qingyi; Go, Vay Liang; Heber, David; Ma, Lili (July 2005), "Inhibition of Growth of Streptococcus mutans, Methicillin-Resistant Staphylococcus aureus, and Vancomycin-Resistant Enterococci by Kurarinone, a Bioactive Flavonoid Isolated from Sophora flavescens", Journal of Clinical Microbiology, 43 (7): 3574–3575, doi:10.1128/JCM.43.7.3574-3575.2005, ISSN 0095-1137, PMC 1169149, PMID 16000511, retrieved November 9, 2016
  2. Fakhimi, Ali; Iranshahi, Mehrdad; Emami, Seyed Ahmad; Amin-Ar-Ramimeh, Esam; Zarrini, Gholamreza; Shahverdi, Ahmad Reza (October 2006), "Sophoraflavanone G from sophora pachycarpa enhanced the antibacterial activity of gentamycin against Staphylococcus aureus", Zeitschrift Fur Naturforschung. C, Journal of Biosciences, 61 (9–10): 769–772, ISSN 0939-5075, PMID 17137127
  3. Yamaki, Masae; Kashihara, Mikiko; Takagi, Shuzo (December 1, 1990), "Activity of Ku Shen compounds against Staphylococcus aureus and Streptococcus mutans", Phytotherapy Research, 4 (6): 235–236, doi:10.1002/ptr.2650040607, ISSN 1099-1573, retrieved November 9, 2016

immunomodulator An immunomodulator is a substance that affects the functioning of the immune system

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From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.