Rotigotine
Rotigotine is a dopamine agonist used for Parkinson's disease and restless leg syndrome (RLS) which is available only as a slow-release transdermal patch applied to the skin.[1][2] Rotigotine is also sold under the brand name Neupro.[1][3] Rotigotine is in the same class of drugs as ropinirole and pramipexole.[4]
Contents
Theory[edit | edit source]
Evidence[edit | edit source]
No clinicial trials have yet been carried out of rotigotine for patients with ME/CFS.
A single study of rotigotine for fibromyalgia had high dropout rates for both the drug and placebo, but did not appear to show a significant improvement in pain or other fibromyalgia symptoms at doses of 4mg or 8mg.[4][5]
There is inconsistent evidence of the effect of rotigotine on fatigue in Parkinson's disease.[6][7]
Clinicians[edit | edit source]
Risks and safety[edit | edit source]
Costs and availability[edit | edit source]
Notable studies[edit | edit source]
- 2007, The use of rotigotine for treatment of reducing signs and symptoms of fibromyalgia in adults. Summary (not peer reviewed)
See also[edit | edit source]
Learn more[edit | edit source]
- Rotigotine - drugs.com
- Rotigotine transdermal - drugs.com
- Rotigotine - MedlinePlus
- Rotigotine - DrugBank Online
References[edit | edit source]
- ↑ 1.01.1 "Rotigotine: Indications, Side Effects, Warnings". Drugs.com. Retrieved February 21, 2022.
- ↑ "Rotigotine Transdermal Advanced Patient Information". Drugs.com. Retrieved February 21, 2022.
- ↑ "Pramipexole: MedlinePlus Drug Information". medlineplus.gov. Retrieved February 21, 2022.
- ↑ 4.04.1 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066139/
- ↑ https://clinicaltrials.gov/ct2/show/results/NCT00464737
- ↑ https://jamanetwork.com/journals/jamaneurology/article-abstract/785048
- ↑ https://n.neurology.org/content/78/1_Supplement/P06.088.short
agonist A chemical that binds to the receptor and stimulates it's function, e.g., morphine is an opioid agonist that binds to the opioid receptor, reducing pain. The opposite of an antagonist.
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