Proton pump inhibitor
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
 | This article is a stub. |
Proton pump inhibitors or PPIs are a class of drugs that reduce levels of stomach acid.[1]
Proton pump inhibitors may be used to treat symptoms of Gastroesophageal Reflux (GERD).
Warning: long term use of PPIs is considered a risk factor for the development of SIBO[2][3] (small intestinal bacterial overgrowth), which has symptoms like fatigue and brain fog that are quite similar to conditions Chronic fatigue syndrome.
Theory
Evidence
Clinicians
Risks and safety
Costs and availability
List of proton pump inhibitors
Proton pump inhibitors include:
- Dexlansoprazole e.g., Dexilant, Kapidex
- Esomeprazole e.g., Nexium
- Pantoprazole e.g., Protonix
- Rabeprazole e.g., Aciphex[1]
Systemic mastocytosis
Proton pump inhibitors for systematic mastocytosis (which is not the same as mast cell activation disorder) include:
- Lansoprazole e.g., Prevacid, which is used for
- Omeprazole e.g., Prilosec[1][4]
See also
Learn more
- Proton pump inhibitors - drugs.com
- drugbank.ca
References
- ↑ 1.0 1.1 1.2 "List of Proton Pump Inhibitors + Uses, Side Effects". Drugs.com. Retrieved February 16, 2021.
- ↑ LO, WAI–KIT; CHAN, Walter W. (2013). "Proton Pump Inhibitor Use and the Risk of Small Intestinal Bacterial Overgrowth: A Meta-analysis". CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (11): 483–490.
- ↑ Su, Tingting; Lai, Sanchuan; Lee, Allen; He, Xingkang; Chen, Shujie (January 2018). "Meta-analysis: proton pump inhibitors moderately increase the risk of small intestinal bacterial overgrowth". Journal of Gastroenterology. 53 (1): 27–36. doi:10.1007/s00535-017-1371-9. ISSN 1435-5922. PMID 28770351.
- ↑ "Medications for Systemic Mastocytosis". Drugs.com. Retrieved February 18, 2021.
