Severe acute respiratory syndrome

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(Redirected from Post-SARS syndrome)

Severe Acute Respiratory Syndrome or SARS is a respiratory viral infection caused by the highly Infectious SARS-CoV coronavirus.[1][2][3] It is a potentially deadly illness that quickly spread around the world in 2003, infecting around 8,000 people, with 9.6% of those infected dying.[1] SARS causes flu-like symptoms.[4]

Symptoms[edit | edit source]

Symptoms are similar to the flu.[4]

About 1 in 5 people with SARS may also get diarrhea.[4]

Symptoms Can Worsen Fast

A dry cough can develop 2 to 7 days into the illness. This cough can keep the body from getting enough oxygen. 1 in 10 people with SARS will need a machine to help them breathe.[4]

Can Lead to Other Health Problems

  • pneumonia
  • heart failure
  • liver failure[4]

People who are over age 60 and have chronic illness like diabetes or hepatitis are most likely to have these problems.[4]

Methods of transmission[edit | edit source]

The coronavirus that causes SARS can be transmitted by droplets containing the virus during close contact, from touching surfaces containing droplets, or from respiratory droplets in the air.[3]
Source: Xiao et al. 2017. PLoS ONE 12(7): e0181558.

Post-SARS syndrome[edit | edit source]

The name post-SARS syndrome or Chronic post-SARS was proposed by Moldofsky et al. (2011) to describe those survivors of the 2003 SARS outbreak who remained too ill to work 8 years later.[5] Moldofsky's described post-SARS syndrome as similar to fibromyalgia and chronic fatigue syndrome, better known as ME/CFS.[5] Post-SARS syndrome was described as chronic (lasting over 6 months), with persistent fatigue, widespread muscle pain, weakness, depression, and unrefreshing sleep with sleep apneas/hypopneas, sleep EEG abnormalities, post-sleep fatigue and post sleep sleepiness. An earlier study found that 27% of hospitalized SARS survivors in Hong Kong met the criteria for ME/CFS six years later, with the illness appearing immediately after patients contacted SARS.[6]

See also
Postviral fatigue syndrome, Long COVID and Fibromyalgia.

ME/CFS[edit | edit source]

Lam et al. (2009) conducted a large long-term follow up of people needing hospital treatment for SARS in Hong Kong, and found that 40% reported chronic fatigue, and 27% of them and met the CDC's criteria for chronic fatigue syndrome, sometimes called ME/CFS, one year after recovery from SARS.[6] This study found that the use of corticosteroids (steroids) in treating SARS was not associated with an increased likelihood of chronic fatigue, and the high rates of psychiatric problems did not explain high rates of chronic fatigue.[6]

Moldofsky et al. (2011) assessed 21 survivors of SARS from Toronto, Canada, who remained too ill to return to work, stating that chronic post-SARS was similar to fibromyalgia.[5]

See also
Myalgic Encephalomyelitis (ME) and Chronic Fatigue Syndrome (CFS).

Notable studies[edit | edit source]

  • 2011, Chronic widespread musculoskeletal pain, fatigue, depression and disordered sleep in chronic post-SARS syndrome; a case-controlled study[5] - (Full text)
  • 2010, Severe Acute Respiratory Syndrome and Coronavirus - (Full text)
  • 2004, Pulmonary function and exercise capacity in survivors of severe acute respiratory syndrome (Full text)
  • 2009, Mental Morbidities and Chronic Fatigue in Severe Acute Respiratory Syndrome Survivors: Long-term Follow-up[6] - (Full text)
  • 2003, Consensus document on the epidemiology of severe acute respiratory syndrome (SARS)[7] - (Full text)

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. ↑ 1.0 1.1 Warnes, Sarah L.; Little, Zoë R.; Keevil, C. William (November 10, 2015). "Human Coronavirus 229E Remains Infectious on Common Touch Surface Materials". mBio. 6 (6). doi:10.1128/mBio.01697-15. ISSN 2150-7511. PMC 4659470. PMID 26556276.
  2. ↑ Hui, David S.C.; Chan, Paul K.S. (September 2010). "Severe Acute Respiratory Syndrome and Coronavirus". Infectious Disease Clinics of North America. 24 (3): 619–638. doi:10.1016/j.idc.2010.04.009. ISSN 0891-5520. PMC 7127710. PMID 20674795.
  3. ↑ 3.0 3.1 Xiao, Shenglan; Li, Yuguo; Wong, Tze-wai; Hui, David S.C. (July 20, 2017). "Role of fomites in SARS transmission during the largest hospital outbreak in Hong Kong". PLOS ONE. 12 (7): e0181558. doi:10.1371/journal.pone.0181558. ISSN 1932-6203. PMC 5519164. PMID 28727803.
  4. ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 "SARS (Severe Acute Respiratory Syndrome): Symptoms, Causes, Treatment". WebMD. Retrieved March 28, 2020.
  5. ↑ 5.0 5.1 5.2 5.3 Moldofsky, Harvey; Patcai, John (March 24, 2011). "Chronic widespread musculoskeletal pain, fatigue, depression and disordered sleep in chronic post-SARS syndrome; a case-controlled study". BMC Neurology. 11 (1): 37. doi:10.1186/1471-2377-11-37. ISSN 1471-2377. PMC 3071317. PMID 21435231.
  6. ↑ 6.0 6.1 6.2 6.3 Lam, Marco Ho-Bun; Wing, Yun-Kwok; Yu, Mandy Wai-Man; Leung, Chi-Ming; Ma, Ronald C.W.; Kong, Alice P.S.; So, W.Y.; Fong, Samson Yat-Yuk; Lam, Siu-Ping (December 14, 2009). "Mental Morbidities and Chronic Fatigue in Severe Acute Respiratory Syndrome Survivors: Long-term Follow-up". Archives of Internal Medicine. 169 (22): 2142–2147. doi:10.1001/archinternmed.2009.384. ISSN 0003-9926.
  7. ↑ World Health Organization (2003). "Consensus document on the epidemiology of severe acute respiratory syndrome (SARS). No. WHO/CDS/CSR/GAR/2003.11" (PDF). World Health Organization.
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