Paul Fisher

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Paul R. Fisher, PhD, Head of Microbiology, Department of Physiology, Anatomy and Microbiology, La Trobe University, Melbourne, Australia. His research interests include the study of neurodegenerative disease, mitochondrial biology, Parkinson's disease and the roles of mitochondria in disease.[1][2]

ME/CFS research[edit | edit source]

Dr Fisher is currently studying mitochondria in plasma and white blood cells from ME/CFS patients.[2]

Notable studies and publications[edit | edit source]

  • 2009, Dictyostelium discoideum—a model for many reasons[3](Abstract)
  • 2019, Pathological Mechanisms Underlying Myalgic Encephalomyelitis/Chronic Fatigue Syndrome[4] - (Full text)
  • 2019, Editorial: Mitochondria in Health and Disease[5] - (Full text)
  • 2020, An Isolated Complex V Inefficiency and Dysregulated Mitochondrial Function in Immortalized Lymphocytes from ME/CFS Patients[6] - (Full text)
  • 2020, Biomedical Insights That Inform the Diagnosis of ME/CFS[7] - (Full Text)
  • 2020, Cell-Based Blood Biomarkers for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome[8] - (Full text)

Talks, blogs and interviews[edit | edit source]

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. "Paul Fisher". scholars.latrobe.edu.au. Retrieved April 23, 2019.
  2. 2.02.12.2 Johnson, Cort (July 18, 2019). "Emerging Insights #II: "The Cellular Equivalent of Chronic Fatigue" Found in ME/CFS". Health Rising. Retrieved July 21, 2019.
  3. Annesley, Sarah J.; Fisher, Paul R. (September 2009). "Dictyostelium discoideum—a model for many reasons". Molecular and Cellular Biochemistry. 329 (1–2): 73–91. doi:10.1007/s11010-009-0111-8. ISSN 0300-8177.
  4. Fisher, Paul R.; Annesley, Sarah J.; Missailidis, Daniel (July 20, 2019). "Pathological Mechanisms Underlying Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". Diagnostics. 9 (3): 80. doi:10.3390/diagnostics9030080.
  5. Annesley, Sarah J.; Fisher, Paul R. (July 5, 2019). "Mitochondria in Health and Disease". Cells. 8 (7): 680. doi:10.3390/cells8070680. ISSN 2073-4409. PMC 6678092. PMID 31284394.
  6. Missailidis, Daniel; Annesley, Sarah; Allan, Claire; Sanislav, Oana; Lidbury, Brett; Lewis, Don; Fisher, Paul (February 6, 2020). "An Isolated Complex V Inefficiency and Dysregulated Mitochondrial Function in Immortalized Lymphocytes from ME/CFS Patients". Int. J. Mol. Sci. 21 (3): 1074. doi:10.3390/ijms21031074. PMC 7036826. PMID 32041178.
  7. Lidbury, Brett A.; Fisher, Paul R. (February 8, 2020). "Biomedical Insights That Inform the Diagnosis of ME/CFS". Diagnostics. 10 (2): 92. doi:10.3390/diagnostics10020092. ISSN 2075-4418.
  8. Missailidis, Daniel; Sanislav, Oana; Allan, Claire Y.; Annesley, Sarah J.; Fisher, Paul R. (February 8, 2020). "Cell-Based Blood Biomarkers for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". International Journal of Molecular Sciences. 21 (3): 1142. doi:10.3390/ijms21031142. ISSN 1422-0067.

myalgic encephalomyelitis (ME) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

mitochondria Important parts of the biological cell, with each mitochondrion encased within a mitochondrial membrane. Mitochondria are best known for their role in energy production, earning them the nickname "the powerhouse of the cell". Mitochondria also participate in the detection of threats and the response to these threats. One of the responses to threats orchestrated by mitochondria is apoptosis, a cell suicide program used by cells when the threat can not be eliminated.

mitochondria Important parts of the biological cell, with each mitochondrion encased within a mitochondrial membrane. Mitochondria are best known for their role in energy production, earning them the nickname "the powerhouse of the cell". Mitochondria also participate in the detection of threats and the response to these threats. One of the responses to threats orchestrated by mitochondria is apoptosis, a cell suicide program used by cells when the threat can not be eliminated.

The information provided at this site is not intended to diagnose or treat any illness.
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