Jakob Theorell

Jakob Theorell, MD, PhD, researches at the Yenan Bryceson Group, based at the Center for Infectious Medicine, in Karolinska Institutet in Stockholm, Sweden with his work focusing on understanding the mechanisms of disease in patients suffering from chronic immunodeficiency syndromes.

Doctorate thesis

• 2017 - Understanding Chronic Immunodeficiency Disorders Through Assessment of Cytotoxic Lymphocyte Function - (Full text)

Notable studies

• 2017 - Unperturbed Cytotoxic Lymphocyte Phenotype and Function in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients - (Full text)

Talks and interviews

• 2017, Speaker at the 12th Invest in ME International ME Conference; Speech title: "Studies of NK cells and cytotoxic T-cells in ME-patients from one Swedish and one Norwegian cohort" - (Video)

Online presence

• ResearchGate

Learn more

• Yenan Bryceson Group Website

myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

T cell A type of white blood cell which is mostly produced or matured in the thymus gland (hence T-cell) and is involved in the adaptive immune response on a cellular level. Also known as a T lymphocyte. (Learn more: www.youtube.com)

See myalgic encephalomyelitis.