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Glymphatic dysfunction hypothesis

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Glymphatic dysfunction hypothesis was developed by Dr. Peter Wostyn in 2018. It postulates that dysfunction of the waste clearance system, called the glymphatic system, causes a build-up of toxins within the central nervous system, which precipitates at least some cases of chronic fatigue syndrome.[1]

Theory[edit | edit source]

Evidence[edit | edit source]

Treatment[edit | edit source]

Dr. Peter Wostyn suggests that at least some chronic fatigue syndrome patients may benefit from cerebrospinal fluid drainage thus restoring glymphatic transport and waste removal from the brain.[1]

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