Glymphatic dysfunction hypothesis

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Glymphatic dysfunction hypothesis was developed by Dr. Peter Wostyn in 2018. It postulates that dysfunction of the waste clearance system, called the glymphatic system, causes a build-up of toxins within the central nervous system, which precipitates at least some cases of chronic fatigue syndrome.[1]

Theory[edit | edit source]

Evidence[edit | edit source]

Treatment[edit | edit source]

Dr. Peter Wostyn suggests that at least some chronic fatigue syndrome patients may benefit from cerebrospinal fluid drainage thus restoring glymphatic transport and waste removal from the brain.[1]

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. ↑ 1.0 1.1 Wostyn, Peter; De Deyn, Peter Paul (September 2018). "The putative glymphatic signature of chronic fatigue syndrome: A new view on the disease pathogenesis and therapy". Medical Hypotheses. 118: 142–145. doi:10.1016/j.mehy.2018.07.007.

central nervous system (CNS) - One of the two parts of the human nervous system, the other part being the peripheral nervous system. The central nervous system consists of the brain and spinal cord, while the peripheral nervous system consists of nerves that travel from the central nervous system into the various organs and tissues of the body.

Retrieved from "https://me-pedia.org/w/index.php?title=Glymphatic_dysfunction_hypothesis&oldid=237426"