Evening primrose oil

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Evening primrose oil supplement. Image: Open Food Facts

Evening primrose oil is a medicinal oil derived from the evening primrose (Oenothera) plant. It is rich in gamma linolenic acid (GLA), an omega 6 essential fatty acid.[1]

Potential uses[edit | edit source]

Theory[edit | edit source]

Evidence[edit | edit source]

ME/CFS[edit | edit source]

Notable studies[edit | edit source]

  • 1996, Cognitive behaviour therapy for the chronic fatigue syndrome. Evening primrose oil and magnesium have been shown to be effective[2](Full text)
  • 2004, The use of eicosapentaenoic acid in the treatment of chronic fatigue syndrome[3](Abstract)
  • 2005, In chronic fatigue syndrome, the decreased levels of omega-3 poly-unsaturated fatty acids are related to lowered serum zinc and defects in T cell activation[4](Full text)
  • 2007, Long-chain polyunsaturated fatty acids and the pathophysiology of myalgic encephalomyelitis (chronic fatigue syndrome)[5](Abstract)

Efamol marine[edit | edit source]

  • 1990, A placebo-controlled trial of n-3, n-6, essential fatty acids in the treatment of postviral fatigue syndrome[6](Abstract)
  • 1999, The role of essential fatty acids in chronic fatigue syndrome: A case‐controlled study of red‐cell membrane essential fatty acids (EFA) and a placebo‐controlled treatment study with high dose of EFA[7](Full text)
Found no overall benefit was found for efamol marine.

Risks and safety[edit | edit source]

Costs and availability[edit | edit source]

Fatty acid blends containing evening primose oil invoice efamol marine, which adds fish oil and overall contains 57% v-linoleic acid, 7.2% GLA, and 3.6% EPAs and 2.4% DHA.[7][4]

See also[edit | edit source]

References[edit | edit source]

serum The clear yellowish fluid that remains from blood plasma after clotting factors have been removed by clot formation. (Blood plasma is simply blood that has had its blood cells removed.)

cell membrane A very thin membrane, composed of lipids and protein, that surrounds the cytoplasm of a cell and controls the passage of substances into and out of the cell.

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.