Choline

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Choline is a major phospholipid and an essential nutrient used as a building block to several other biochemicals in the human body.[1] Although the body manufactures some choline, the majority of what is used needs to be consumed in food, such as eggs, meat, poultry, fish, cruciferous vegetables, peanuts, and dairy products.[2]

Purpose

Choline is used to produce the neurotransmitter acetylcholine.[1]

Sources

Although some choline can be made by the human body, dietary choline is also needed. Men deficient in choline have been found to develop liver and muscle damage, and have compromised kidney function.[1]

Choline is found in many different foods, including:

  • beef liver
  • egg
  • bacon
  • cod
  • dairy products
  • vegetarian and vegan sources include wheatgerm, soy beans and tofu, peanut butter, bread and spinach[1]

ME/CFS

Chemical formula

C
5
H
14
NO+
[3]

Supplements

Choline supplements include CDP-choline (citicoline), choline chloride, choline bitartrate, and other choline salts.[2]

Phosphatidylcholine (PC) can be used to treat choline deficiency.[1]

See also

Learn more

References

  1. 1.0 1.1 1.2 1.3 1.4 van der Poll, MCG; Luiking, YC; Dejong, CHC; Soeters, PB (September 2, 2009). "Amino Acids". In Caballero, Benjamin (ed.). Guide to Nutritional Supplements. Oxford, UK: Academic Press. pp. 108–109. ISBN 978-0-12-375661-9.
  2. 2.0 2.1 "Choline". Linus Pauling Institute. April 28, 2014. Retrieved May 3, 2019.
  3. PubChem. "Choline". pubchem.ncbi.nlm.nih.gov. Retrieved May 3, 2019.