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Choline is a molecule used as a building block to several other biochemicals in the human body. Although the body manufactures some choline, the majority of what is used needs to be consumed in food, such as eggs, meat, poultry, fish, cruciferous vegetables, peanuts, and dairy products.[1]

A small study of CFS patients found increased choline in the basal ganglia,[2] another in the occipital cortex.[3]

Increased choline has been found in the certain brain structures of CFS patients, suggesting a possible increased oxidation of the cell membranes of neurons in these regions.[2][3][4]

Chemical formula[edit | edit source]


Supplements[edit | edit source]

Choline supplements include CDP-choline (citicoline), choline chloride, choline bitartrate, and other Choline salts.[1]

Learn more[edit | edit source]

References[edit | edit source]

  1. 1.01.1 "Choline". Linus Pauling Institute. Apr 28, 2014. Retrieved May 3, 2019. 
  2. 2.02.1 Chaudhuri, A.; Condon, B. R.; Gow, J. W.; Brennan, D.; Hadley, D. M. (Feb 10, 2003), "Proton magnetic resonance spectroscopy of basal ganglia in chronic fatigue syndrome", Neuroreport, 14 (2): 225–228, doi:10.1097/01.wnr.0000054960.21656.64, ISSN 0959-4965, PMID 12598734 
  3. 3.03.1 Puri, B. K.; Counsell, S. J.; Zaman, R.; Main, J.; Collins, A. G.; Hajnal, J. V.; Davey, N. J. (Sep 1, 2002), "Relative increase in choline in the occipital cortex in chronic fatigue syndrome", Acta Psychiatrica Scandinavica, 106 (3): 224–226, doi:10.1034/j.1600-0447.2002.01300.x, ISSN 1600-0447, retrieved Nov 9, 2016 
  4. Puri, B. K (April 2004), "The use of eicosapentaenoic acid in the treatment of chronic fatigue syndrome", Prostaglandins, Leukotrienes and Essential Fatty Acids, Professor David F. Horrobin 1939-2003: A Tribute, 70 (4): 399–401, doi:10.1016/j.plefa.2003.12.015, ISSN 0952-3278, retrieved Nov 9, 2016 
  5. PubChem. "Choline". Retrieved May 3, 2019. 

cell membrane - A very thin membrane, composed of lipids and protein, that surrounds the cytoplasm of a cell and controls the passage of substances into and out of the cell.

chronic fatigue syndrome (CFS) - A controversial term, invented by the U.S. Centers for Disease Control, that generally refers to a collection of symptoms as “fatigue”. There have been multiple attempts to come up with a set of diagnostic criteria to define this term, but few of those diagnostic criteria are currently in use. Previous attempts to define this term include the Fukuda criteria and the Oxford criteria. Some view the term as a useful diagnostic category for people with long-term fatigue of unexplained origin. Others view the term as a derogatory term borne out of animus towards patients. Some view the term as a synonym of myalgic encephalomyelitis, while others view myalgic encephalomyelitis as a distinct disease.

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.