Bragee ME center Stockholm
Bragee ME center in Stockholm, Sweden, was a private and specialized clinic endorsed by the Stockholm County region to help patients with ME/CFS.[1] The clinic was a national resource with patients from all over Sweden, but seized their clinical activities late 2023. Scientific engagements within the field persist (see below).
History[edit | edit source]
Bragee ME center started in 2018. By February 2022 around 1600 patients with ME/CFS were registered at the clinic, all diagnosed according to the Canadian Consensus Criteria (CCC). Local political initiatives in the Stockholm county resulted in closure of the clinic in December 2023 and patients are since then taken care of by primary care centers.
Staff[edit | edit source]
The center had around 35 employees within various professions, of whom many with scientific experience (PhDs, Associate professors, and Professors).
Aims[edit | edit source]
The clinic, and its staff, had the ambition to develop the clinical care of individuals with ME/CFS and improve understanding of the disease, which included scientific engagements.
Research[edit | edit source]
In 2018, representatives of the clinic initiated the research network PIAF (Pain Inflammation And Fatigue) with monthly meetings at which multinational speakers are invited to present their latest findings and hypotheses in relation to ME/CFS (NB. restricted access, invitation needed). Those meeting are presently at hold.
Two clinical pilot studies were finalized before closing the clinic, and the results from those two studies have been published in scientific peer-reviewed journals (see below). Furthermore, several ongoing scientific projects are ongoing including studies with external collaborators, partly by providing biological material from patients with ME/CFS, following existing ethical regulations including informed consent.
A study supported by the Patient Led Research Col (PLRC) and OMF are currently ongoing (October 2025) that intends to evaluate the clinical outcome of cervical spinal surgery in patients with ME/CFS and radiculopathy.
Notable studies[edit | edit source]
- 2020, Intracranial Hypertension, Hypermobility, and Craniocervical Obstructions in Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome[2] - (Abstract)
- 2022, Saliva antibody-fingerprint of reactivated latent viruses after mild/asymptomatic COVID-19 is unique in patients with myalgic-encephalomyelitis/chronic fatigue syndrome[3]
- 2024, Successful Subcutaneous Immunoglobulin Therapy in a Case Series of Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome[4]
- 2025, Beneficial effects of intermittent intravenous saline infusion in dysautonomic patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: a case-series[5]
Online presence[edit | edit source]
- Website, in Swedish)
See also[edit | edit source]
References[edit | edit source]
- ↑ "Rehab för smärta, utmattning och ME/CFS". Bragee Kliniker (in svenska). Retrieved February 21, 2022.
- ↑ Bragée, Björn; Michos, Anastasios; Drum, Brandon; Fahlgren, Mikael; Szulkin, Robert; Bertilson, Bo C. (2020). "Signs of Intracranial Hypertension, Hypermobility, and Craniocervical Obstructions in Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". Frontiers in Neurology. 11. doi:10.3389/fneur.2020.00828. ISSN 1664-2295. PMC 7485557. PMID 32982905.
- ↑ Apostolou, Eirini; Rizwan, Muhammad; Moustardas, Petros; Sjögren, Per; Bertilson, Bo Christer; Bragée, Björn; Polo, Olli; Rosén, Anders (October 20, 2022). "Saliva antibody-fingerprint of reactivated latent viruses after mild/asymptomatic COVID-19 is unique in patients with myalgic-encephalomyelitis/chronic fatigue syndrome". Frontiers in Immunology. 13: 949787. doi:10.3389/fimmu.2022.949787. ISSN 1664-3224. PMC 9630598. PMID 36341457.
- ↑ Sjogren, Per; Bragée, Bjorn; Britton, Sven (2024-07). "Successful Subcutaneous Immunoglobulin Therapy in a Case Series of Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". Clinical Therapeutics. 46 (7): 597–600. doi:10.1016/j.clinthera.2024.05.010. ISSN 0149-2918. Check date values in:
|date=(help) - ↑ "Beneficial effects of intermittent intravenous saline infusion in dysautonomic patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: a case-series". Front Neurol. 2025 Jul 21;16:1601599. doi: 10.3389/fneur.2025.1601599. eCollection 2025.
