This page was created by volunteers like you!
Help us make it even better. To learn more about contributing to MEpedia, click here.

Aspirin

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Aspirin tablets with a glass of water

Aspirin, also known as acetylsalicylic acid, is a medication used to treat pain, fever, and inflammation.[1] For pain or fever, effects typically begin within 30 minutes. Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) and works similar to other NSAIDs but also suppresses the normal functioning of platelets. Unlike other NSAIDs, aspirin irreversibly inhibits cyclooxygenase-1 (COX-1) and alters cyclooxygenase-2 (COX-2) in platelets, which leads to inhibition of clotting.[2]

Mast cell diseases

Aspirin may also be used as a mast cell stabilizer for people with MCAD or MCAS, but people with high prostaglandin levels must have this supervised by a physician.[3]

Side Effects

Commonly reported sides effects include[4][5][6]:

  • Indigestion and stomach aches
  • Bleeding and bruising more easily
  • Nausea and vomiting
  • Drowsiness and mild headache

Adverse effects include:

  • Long-lasting pain and swelling
  • Ringing in ears or problems hearing
  • Bloody, tarry stool (melena) or vomiting blood or dark material that looks like coffe grounds (hematemesis)
  • Itchy rashes

See also

Learn more

References

  1. "Aspirin". drugs.com. Retrieved February 17, 2021.
  2. Arif H, Patel P. Salicylic Acid (Aspirin) [Updated 2026 Jun 25]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK519032/
  3. "Medications to Treat Mast Cell Diseases". The Mast Cell Disease Society. Retrieved February 16, 2021.
  4. https://www.nhsinform.scot/tests-and-treatments/medicines-and-medical-aids/types-of-medicine/aspirin/
  5. https://www.nationwidechildrens.org/family-resources-education/health-wellness-and-safety-resources/helping-hands/aspirin
  6. https://www.drugs.com/aspirin.html