Tramadol: Difference between revisions
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It is used for moderate to moderately severe pain, and pain after surgery. The extended release or long acting form is used on chronic pain.<ref>[http://www.mayoclinic.org/drugs-supplements/tramadol-oral-route/description/drg-20068050 Tramadol - Mayo Clinic]</ref> | It is used for moderate to moderately severe pain, and pain after surgery. The extended release or long acting form is used on chronic pain.<ref>[http://www.mayoclinic.org/drugs-supplements/tramadol-oral-route/description/drg-20068050 Tramadol - Mayo Clinic]</ref> | ||
A three-year study showed a correlation between tramadol consumption and [[seizure]] occurrence.<ref name=":0">{{Cite journal|last=Boostani | first = Reza | last2 = Derakhshan | first2 = Siavash| date = 2012 |title=Tramadol induced seizure: A 3-year study|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755854/|journal=Caspian Journal of Internal Medicine|volume=3|issue=3|pages=484–487|issn=2008-6164|pmc=3755854|pmid=24009919}}</ref> | A three-year study showed a correlation between tramadol consumption and [[seizure]] occurrence.<ref name=":0">{{Cite journal | last =Boostani | first = Reza | last2 = Derakhshan | first2 = Siavash| date = 2012 |title=Tramadol induced seizure: A 3-year study|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755854/|journal=Caspian Journal of Internal Medicine|volume=3|issue=3|pages=484–487|issn=2008-6164|pmc=3755854|pmid=24009919}}</ref> | ||
== Notable studies == | == Notable studies == | ||
Revision as of 00:40, March 4, 2023
Tramadol is a generic pain reliever drug used in the United States. The US brand names are: ConZip, FusePaq Synapryn, rybix ODT, Ryzolt, Ultram and Ultram ER. Unlike traditional opioids, tramadol exerts its effects through a combination of serotonergic and opioid mechanisms, and is thought to be less habit-forming. At high doses it also has noradrenergic effects. Sleep disturbances are commonly reported if taken too close to bedtime, and with the extended-release versions.
It is used for moderate to moderately severe pain, and pain after surgery. The extended release or long acting form is used on chronic pain.[1]
A three-year study showed a correlation between tramadol consumption and seizure occurrence.[2]
Notable studies
"In our study, it was seen that seizures occurred both at therapeutic and supratherapeutic ranges without history of epilepsy."[2]
"Conclusion: In conclusion, the neurotoxicity of tramadol commonly manifests as generalized tonic-clonic seizures, most frequently within 24 hours after tramadol intake, and was more common in subjects concomitantly consuming alcohol, illicit drugs, anti-psychotics, or anti-depressants."[2]
See also
Learn more
- Low dose naltrexone (Naltrexone) will block opioids. (Answers to FAQ About Naltrexone Treatment for Alcoholism - 10. Can I take other medications with naltrexone?)
