Altitude: Difference between revisions
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Physical changes at high altitude after full acclimatization has been achieved include reduced production of [[lactate]] post-exercise,<ref name="paradox">{{Cite journal| issn = 1548-9213| volume = 17| issue = 3| pages = 122–126| last1 = Hochachka | first1 = P. W. | last2 = Beatty | first2 = C. L. | last3 = Burelle | first3 = Y. | last4 = Trump | first4 = M. E. | last5 = McKenzie | first5 = D.C. | last6 = Matheson | first6 = G. O.| title = The Lactate Paradox in Human High-Altitude Physiological Performance| journal = Physiology| access-date = 2016-11-09| date = 2002-06-01| url = https://physiologyonline.physiology.org/content/17/3/122| pmid = 12021383}}</ref> increased tissue [[carbon dioxide]], increased [[red blood cell]] mass, increased [[hematocrit]], decreased [[plasma]] volume, a higher concentration of capillaries in skeletal muscles, increased [[myoglobin]], increased [[Mitochondrion|mitochondria]], increased [[aerobic]] enzyme concentration, increase in [[2,3-Bisphosphoglyceric acid]], hypoxic pulmonary vasoconstriction, and right ventricular hypertrophy. | Physical changes at high altitude after full acclimatization has been achieved include reduced production of [[lactate]] post-exercise,<ref name="paradox">{{Cite journal| issn = 1548-9213| volume = 17 | issue = 3| pages = 122–126| last1 = Hochachka | first1 = P.W. | last2 = Beatty | first2 = C.L. | last3 = Burelle | first3 = Y. | last4 = Trump | first4 = M.E. | last5 = McKenzie | first5 = D.C. | last6 = Matheson | first6 = G.O. |title = The Lactate Paradox in Human High-Altitude Physiological Performance| journal = Physiology| access-date = 2016-11-09| date = 2002-06-01| url = https://physiologyonline.physiology.org/content/17/3/122 | pmid = 12021383}}</ref> increased tissue [[carbon dioxide]], increased [[red blood cell]] mass, increased [[hematocrit]], decreased [[plasma]] volume, a higher concentration of capillaries in skeletal muscles, increased [[myoglobin]], increased [[Mitochondrion|mitochondria]], increased [[aerobic]] enzyme concentration, increase in [[2,3-Bisphosphoglyceric acid]], hypoxic pulmonary vasoconstriction, and right ventricular hypertrophy. | ||
The decreased lactate production at altitude is called the "lactate paradox." | The decreased lactate production at altitude is called the "lactate paradox." | ||
Latest revision as of 00:28, April 2, 2023
Physical changes at high altitude after full acclimatization has been achieved include reduced production of lactate post-exercise,[1] increased tissue carbon dioxide, increased red blood cell mass, increased hematocrit, decreased plasma volume, a higher concentration of capillaries in skeletal muscles, increased myoglobin, increased mitochondria, increased aerobic enzyme concentration, increase in 2,3-Bisphosphoglyceric acid, hypoxic pulmonary vasoconstriction, and right ventricular hypertrophy.
The decreased lactate production at altitude is called the "lactate paradox."
