T cell immunoreceptor with Ig and ITIM domains

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TIGIT or T Cell Immunoreceptor With Ig And ITIM Domains is a protein and antibody which has an important role in the immune system.[1][2] The gene that encodes the TIGIT antibody may also be referred to as TIGIT.[3]

Function[edit | edit source]

TIGIT is an emerging immune checkpoint, and a number of drugs targeting TIGIT are undergoing clinical trials for a number of types of cancer.[3][2]

ME/CFS[edit | edit source]

See also
Genetics of chronic fatigue syndrome.

Fibromyalgia[edit | edit source]

A 2021 study by Verma et al. using immune profiling that TIGIT may have an important role in fibromyalgia.[1]

Notable studies[edit | edit source]

  • 2021, Unbiased immune profiling reveals a natural killer cell-peripheral nerve axis in fibromyalgia[1] - (Abstract)

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. ↑ 1.0 1.1 1.2 https://journals.lww.com/pain/abstract/9000/unbiased_immune_profiling_reveals_a_natural_killer.97873.aspx
  2. ↑ 2.0 2.1 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160651/
  3. ↑ 3.0 3.1 "T cell immunoreceptor with Ig and ITIM domains - Gene card". Gene cards. Retrieved May 1, 2022.

T cell A type of white blood cell which is mostly produced or matured in the thymus gland (hence T-cell) and is involved in the adaptive immune response on a cellular level. Also known as a T lymphocyte. (Learn more: www.youtube.com)

antibodies Antibody/immunoglobulin refers to any of a large number of specific proteins produced by B cells that act against an antigen in an immune response.

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