Isocitrate dehydrogenase: Difference between revisions

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==ME/CFS ==
==ME/CFS ==
A small study by Sweetman et al. (2020) found that IDH2 expression was decreased in patients with ME/CFS compared to healthy controls.<ref name=Sweetman2020>{{Cite journal|last=Sweetman|first=Eiren|author-link=|last2=Kleffmann|first2=Torsten|author-link2=|last3=Edgar|first3=Christina|author-link3=|last4=de Lange|first4=Michel|author-link4=|last5=Vallings|first5=Rosamund|author-link5=Rosamund Vallings|last6=Tate|first6=Warren|author-link6=Warren Tate|last7=|first7=|last8=|first8=|date=2020-09-24|title=A SWATH-MS analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction|url=https://doi.org/10.1186/s12967-020-02533-3|journal=Journal of Translational Medicine|volume=18|issue=1|pages=365|doi=10.1186/s12967-020-02533-3|issn=1479-5876|pmc=PMC7512220|pmid=|access-date=|quote=|via=}}</ref>
A small study by Sweetman et al. (2020) found that IDH2 expression was decreased in patients with ME/CFS compared to healthy controls.<ref name=Sweetman2020>{{Cite journal|last=Sweetman|first=Eiren|author-link=|last2=Kleffmann|first2=Torsten|author-link2=|last3=Edgar|first3=Christina|author-link3=|last4=de Lange|first4=Michel|author-link4=|last5=Vallings|first5=Rosamund|author-link5=Rosamund Vallings|last6=Tate|first6=Warren|author-link6=Warren Tate|last7=|first7=|last8=|first8=|date=2020-09-24|title=A SWATH-MS analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction|url=https://doi.org/10.1186/s12967-020-02533-3|journal=Journal of Translational Medicine|volume=18|issue=1|pages=365|doi=10.1186/s12967-020-02533-3|issn=1479-5876|pmc=PMC7512220|pmid=|access-date=|quote=|via=}}</ref>
==Learn more ==
*[[Citric acid cycle]]


==References ==
==References ==

Revision as of 19:00, September 26, 2020

Isocitrate dehydrogenase NADP+ or IDH2 is a protein involved in the citric acid (TCA) cycle function.

ME/CFS[edit | edit source]

A small study by Sweetman et al. (2020) found that IDH2 expression was decreased in patients with ME/CFS compared to healthy controls.[1]

Learn more[edit | edit source]

References[edit | edit source]

  1. Sweetman, Eiren; Kleffmann, Torsten; Edgar, Christina; de Lange, Michel; Vallings, Rosamund; Tate, Warren (September 24, 2020). "A SWATH-MS analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction". Journal of Translational Medicine. 18 (1): 365. doi:10.1186/s12967-020-02533-3. ISSN 1479-5876. PMC 7512220.