Coxsackievirus B4

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Coxsackievirus B4 is a Coxsackie B enterovirus that belong to the Picornaviridae family.

Coxsackievirus B4 has a cell tropism for natural killer cells and pancreatic islet cells.

Type 1 Diabetes[edit | edit source]

Several studies have suggested a relationship between Coxsackie B4 and the onset of Type 1 diabetes.[1][2][3]

A study of patients with Type 1 Diabetes found that Coxsackie B4 was found to infect the β cells in the pancreatic islets of the pancreas and cause inflammation mediated by natural killer cells.[4]

Treatment[edit | edit source]

Several compounds have been found in in vitro or animals studies to have antiviral activity for Coxsackie B4 including arbidol,[5] Yakammaoto[6], raoulic acid[7], emodin[8] Epimedium, and Azadirachta indica (Neem).[9] However, none of these compounds have been evaluated in human trials.

See also[edit | edit source]

References[edit | edit source]


The information provided at this site is not intended to diagnose or treat any illness.

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history