Coxsackievirus B4 is an enterovirus that belong to the Picornaviridae family.
Coxsackievirus B4 has a cell tropism for natural killer cells and pancreatic islet cells
Type 1 Diabetes
Several studies have suggested a relationship between Coxsackie B4 and the onset of Type 1 diabetes.
A study of patients with Type 1 Diabetes found that Coxsackie B4 was found to infect β cells and cause inflammation mediated by natural killer cells.
- ↑ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1587352/
- ↑ http://link.springer.com/article/10.1007%2Fs00125-003-1297-z
- ↑ http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0057729
- ↑ http://www.pnas.org/content/104/12/5115.full
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