Coxsackievirus B4 has a cell tropism for natural killer cells and pancreatic islet cells.
Type 1 Diabetes[edit | edit source]
Treatment[edit | edit source]
Several compounds have been found in in vitro or animals studies to have antiviral activity for Coxsackie B4 including arbidol, Yakammaoto, raoulic acid, emodin Epimedium, and Azadirachta indica (Neem). However, none of these compounds have been evaluated in human trials.
See also[edit | edit source]
References[edit | edit source]
- Zhang, S (May 2017). "Umifenovir effectively inhibits IL-10 dependent persistent Coxsackie B4 virus infection". Antiviral Research. 141: 165–173.
- Choi, HJ (January 2009). "Antiviral activity of raoulic acid from Raoulia australis against Picornaviruses". Phytomedicine.
- Liu, Zhao (October 2013). "In Vitro and in Vivo Studies of the Inhibitory Effects of Emodin Isolated from Polygonum cuspidatum on Coxsakievirus B-4". Molecules.
- Badam, L (1999). "'In vitro' antiviral activity of neem (Azadirachta indica. A. Juss) leaf extract against group B coxsackieviruses." J Commun Dis.