Neuro-Inflammatory and Oxidative Fatigue
Neuro-Inflammatory and Oxidative Fatigue (NIOF) is a name and case definition proposed by Michael Maes in 2015. In his paper the author stated "The aim of the present study was to delineate a new case definition of ME/CFS based on pattern recognition methods and using neuro-immune, inflammatory, oxidative and nitrosative stress (neuro-IO&NS) biomarkers as external validating criteria".
Media Coverage[edit | edit source]
- 2015, Study Proposes New Name, Definition and Biomarkers (#MEAction, December 5 2015)
References[edit | edit source]
- Maes, Michael (2015). "A new case definition of Neuro-Inflammatory and Oxidative Fatigue (NIOF), a neuroprogressive disorder, formerly known as chronic fatigue syndrome or Myalgic Encephalomyelitis: results of multivariate pattern recognition methods and external validation by neuro-immune biomarkers". Neuro Endocrinology Letters. 36 (4): 320–329. ISSN 0172-780X. PMID 26454487.