Neuronal PAS domain protein 2

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Neuronal PAS domain protein 2 or NPAS2.[1]

Function[edit | edit source]

ME/CFS[edit | edit source]

NPAS2 is considered to be the master "body clock" gene, that regulates the circadian rhythm.[2]

Notable studies[edit | edit source]

  • 2022, Circadian rhythm disruption in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Implications for the post-acute sequelae of COVID-19[2] - (Full text)
  • 2011, Convergent Genomic Studies Identify Association of GRIK2 and NPAS2 with Chronic Fatigue Syndrome[3] - (Full text)

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. ↑ "NPAS2 Gene card". Gene cards. Retrieved March 18, 2022.
  2. ↑ 2.0 2.1 McCarthy, Michael J. (March 1, 2022). "Circadian rhythm disruption in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Implications for the post-acute sequelae of COVID-19". Brain, Behavior, & Immunity - Health. 20 (5): 100412. doi:10.1016/j.bbih.2022.100412. ISSN 2666-3546.
  3. ↑ Smith, Alicia K.; Fang, Hong; Whistler, Toni; Unger, Elizabeth R.; Rajeevan, Mangalathu S. (2011). "Convergent Genomic Studies Identify Association of GRIK2 and NPAS2 with Chronic Fatigue Syndrome". Neuropsychobiology. 64 (4): 183–194. doi:10.1159/000326692. ISSN 0302-282X. PMC 3701888. PMID 21912186.
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