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(Redirected from L-glutamine)

Glutamine, also known as L-glutamine,[1] is the most abundant free amino acid circulating in the blood as well as stored in the skeletal muscles. Since it can be made by the human body, it is considered a "non-essential" amino acid. Glutamine is a diverse amino acid that is utilized in numerous vital functions. It is necessary for rapidly dividing cells, including those of the gut and immune system. Glutamine is sometimes used by the mitochondria in energy production and is a precursor to the neurotransmitter, glutamate. Glutamate is perhaps best known as the most common excitatory neurotransmitter, and under normal conditions it plays an important role in learning and memory.

Patients who are concerned about increased intestinal permeability (AKA leaky gut) often supplement with L-glutamine as it is thought to help repair the intestinal tract. Leaky gut is thought by these patients to contribute to fatigue and inflammation.

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  1. Pubchem. "Glutamine". Retrieved November 17, 2018.