Jos van der Meer

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Jos W.M. van der Meer, MD, PhD, is emeritus professor and former Head of the Department of General Internal Medicine, of the Radboud University Nijmegen Medical Centre in Nijmegen, Netherlands. His professional achievements include serving as Vice president of the Royal Netherlands Academy of Arts and Sciences from 2006 - 2011; Chairman of Natural Science Division of the Royal Netherlands Academy of Arts and Sciences; and being a member of the Academia Europaea (Academy of Europe).[1]

His special interests include: Natural immunity, Cytokines, Autoinflammatory disorders, Hyper-IgD syndrome, Chronic fatigue syndrome, and Antibiotic stewardship.[2]

Notable studies[edit | edit source]

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Online presence[edit | edit source]

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References[edit | edit source]

  3. Vercoulen, J. H. M. M; Swanink, C. M. A; Galama, J. M. D; Fennis, J. F. M; Jongen, P. J. H; Hommes, O. R; van der Meer, J. W. M; Bleijenberg, G (Dec 1, 1998). "The persistence of fatigue in chronic fatigue syndrome and multiple sclerosis: Development of a model". Journal of Psychosomatic Research. 45 (6): 507–517. doi:10.1016/S0022-3999(98)00023-3. ISSN 0022-3999. 
  4. Prins, Judith B.; Bleijenberg, Gijs; Rouweler, Eufride Klein; van Weel, Chris; van der Meer, Jos W. M. (2000), "Doctor-Patient Relationship in Primary Care of Chronic Fatigue Syndrome", Journal of Chronic Fatigue Syndrome, 7 (4): 3-15, doi:10.1300/J092v07n04_02 
  5. Keijmel SP, Saxe J, van der Meer JW, Nikolaus S, Netea MG, Bleijenberg G, Bleeker-Rovers CP, Knoop H. (2015) A comparison of patients with Q fever fatigue syndrome and patients with chronic fatigue syndrome with a focus on inflammatory markers and possible fatigue perpetuating cognitions and behaviour. Journal of Psychosomatic Research 79(4):295-302. doi: 10.1016 Retrieved from
  6. Roerink, M. E.; Lenders, J. W.; Schmits, I. C.; Pistorius, A. M.; Smit, J. W.; Knoop, H.; van der Meer, J. W. M. (2016), "Postural orthostatic tachycardia is not a useful diagnostic marker for chronic fatigue syndrome", Journal of Internal Medicine, doi:10.1111/joim.12564, PMID 27696568 
  7. Roerink, M. E., Knoop, H., Bronkhorst, E. M., Mouthaan, H. A., Hawinkels, L. J. A. C., Joosten, L. A. B., & van der Meer, J. W. M. (2017). Cytokine signatures in chronic fatigue syndrome patients: a Case Control Study and the effect of anakinra treatment. Journal of Translational Medicine, 15, 267.
  8. Janse A, Nikolaus S, Wiborg JF, Heins M, van der Meer JWM, Bleijenberg G, Tummers M, Twisk J, Knoop H. (2017). Long-term follow-up after cognitive behaviour therapy for chronic fatigue syndrome. J Psychosom Res. 2017 Jun;97:45-51. doi: 10.1016/j.jpsychores.2017.03.016.
  9. Roerink ME, Bredie SJH, Heijnen M, Dinarello CA, Knoop H, Van der Meer JWM. (2017). Cytokine Inhibition in Patients With Chronic Fatigue Syndrome: A Randomized Trial. Annals of Intern Med. 2017 Apr 18;166(8):557-564. doi: 10.7326/M16-2391
  10. van der Schaaf ME, De Lange FP, Schmits IC, Geurts DEM, Roelofs K, van der Meer JWM, Toni I, Knoop H. (2017). Prefrontal Structure Varies as a Function of Pain Symptoms in Chronic Fatigue Syndrome. Biological Psychiatry. 2017 Feb 15;81(4):358-365. doi: 10.1016/j.biopsych.2016.07.016.
  11. Roerink, Megan E.; Roerink, Sean H.P.P.; Skoluda, Nadine; van der Schaaf, Marieke E.; Hermus, Ad R.M.M.; van der Meer, Jos W. M.; Knoop, Hans; Nater, Urs M. (2018), "Hair and salivary cortisol in a cohort of women with chronic fatigue syndrome", Hormones and Behavior, 103: 1–6, doi:10.1016/j.yhbeh.2018.05.016 
  12. van der Schaaf ME, Roelofs K, de Lange FP, Geurts DEM, van der Meer JWM, Knoop H, Toni I. (2018). Fatigue Is Associated With Altered Monitoring and Preparation of Physical Effort in Patients With Chronic Fatigue Syndrome. Biol Psychiatry Cogn Neurosci Neuroimaging. 2018 Apr;3(4):392-404. doi: 10.1016/j.bpsc.2018.01.015.
  13. Raijmakers, Ruud P.H.; Koeken, Valerie A.C.M.; Jansen, Anne F.M.; Keijmel, Stephan P.; Roerink, Megan E.; Joosten, Leo A.B.; Netea, Mihai G.; van der Meer, Jos W.M.; Bleeker-Rovers, Chantal P. (Jan 2019). "Cytokine profiles in patients with Q fever fatigue syndrome". Journal of Infection. doi:10.1016/j.jinf.2019.01.006. 
  14. Breukers, Evi M.C.; Raijmakers, Ruud P.H.; Nieuwkerk, P.T.; Bleijenberg, Gijs; van der Meer, Jos W.M.; Bleeker-Rovers, Chantal P.; Keijmel, Stephan P.; Knoop, Hans (Dec 2019). "Mediation analysis shows that a decline in self-efficacy mediates the increase in fatigue severity following an initial positive response to cognitive behavioural therapy in Q fever fatigue syndrome". Journal of Psychosomatic Research. 127: 109841. doi:10.1016/j.jpsychores.2019.109841. 

Cognition - Thought processes, including attention, reasoning, and memory.

Cognitive behavioral therapy (CBT) - A type of psychotherapy geared toward modifying alleged unhealthy thinking, behaviors or illness beliefs. One of the treatment arms used in the controversial PACE trial.

Tachycardia - An unusually rapid heart beat. Can be caused by exercise or illness. A symptom of postural orthostatic tachycardia syndrome (POTS). (Learn more:

Myalgic encephalomyelitis (ME) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.