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In biology, the extracellular matrix (ECM) is a three-dimensional network of extracellular macromolecules, such as collagen, enzymes, and glycoproteins, that provide structural and biochemical support of surrounding cells.
Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.
See also[edit | edit source]
References[edit | edit source]
- Theocharis AD, Skandalis SS, Gialeli C, Karamanos NK (February 2016). "Extracellular matrix structure". Advanced Drug Delivery Reviews. 97: 4–27. doi:10.1016/j.addr.2015.11.001. PMID 26562801.
- Bonnans C, Chou J, Werb Z (December 2014). "Remodelling the extracellular matrix in development and disease". Nature Reviews. Molecular Cell Biology. 15 (12): 786–801. doi:10.1038/nrm3904. PMC 4316204. PMID 25415508.
- Michel G, Tonon T, Scornet D, Cock JM, Kloareg B (October 2010). "The cell wall polysaccharide metabolism of the brown alga Ectocarpus siliculosus. Insights into the evolution of extracellular matrix polysaccharides in Eukaryotes". The New Phytologist. 188 (1): 82–97. doi:10.1111/j.1469-8137.2010.03374.x. PMID 20618907.
- Abedin M, King N (December 2010). "Diverse evolutionary paths to cell adhesion". Trends in Cell Biology. 20 (12): 734–42. doi:10.1016/j.tcb.2010.08.002. PMC 2991404. PMID 20817460.
eukaryote any cell or organism that possesses a clearly defined nucleus, unlike bacteria. Eukaryotes include yeast, fungus, plants, and animals.