Abhijit Chaudhuri and Peter Behan proposed that chronic fatigue syndrome was an acquired neurological channelopathy illness, meaning that the symptoms are the result of ion channel transportation problems affecting the body's nervous system. The channelopathy hypothosis was first published in 1999.
Theory[edit | edit source]
Evidence[edit | edit source]
Notable studies[edit | edit source]
- 1999, Chronic fatigue syndrome is an acquired neurological channelopathy
- 2000, The symptoms of chronic fatigue syndrome are related to abnormal ion channel function
- 2003, Monitoring a Hypothetical Channelopathy in Chronic Fatigue Syndrome: Preliminary Observations
Treatment[edit | edit source]
See also[edit | edit source]
Learn more[edit | edit source]
References[edit | edit source]
- Chaudhuri, Abhijit; Behan, Peter O. (Jan 1, 1999). "Chronic fatigue syndrome is an acquired neurological channelopathy". Human Psychopharmacology: Clinical and Experimental. 14 (1). doi:10.1002/(sici)1099-1077(199901)14:1. ISSN 1099-1077.
- Chaudhuri, A.; Watson, W.S.; Pearn, J.; Behan, P.O. (Jan 2000). "The symptoms of chronic fatigue syndrome are related to abnormal ion channel function" (PDF). Medical Hypotheses. 54 (1): 59–63. doi:10.1054/mehy.1998.0822. ISSN 0306-9877.
- Nijs, Jo; De Becker, Pascale; Demanet, Christian; McGregor, Neil R.; Englebienne, Patrick; Verhas, Michel; De Meirleir, Kenny (Jan 2003). "Monitoring a Hypothetical Channelopathy in Chronic Fatigue Syndrome" (PDF). Journal of Chronic Fatigue Syndrome. 11 (1): 117–133. doi:10.1300/j092v11n01_03. ISSN 1057-3321.
chronic fatigue syndrome (CFS) - A controversial term, invented by the U.S. Centers for Disease Control, that generally refers to a collection of symptoms as “fatigue”. There have been multiple attempts to come up with a set of diagnostic criteria to define this term, but few of those diagnostic criteria are currently in use. Previous attempts to define this term include the Fukuda criteria and the Oxford criteria. Some view the term as a useful diagnostic category for people with long-term fatigue of unexplained origin. Others view the term as a derogatory term borne out of animus towards patients. Some view the term as a synonym of myalgic encephalomyelitis, while others view myalgic encephalomyelitis as a distinct disease.