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Channelopathy hypothesis
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Abhijit Chaudhuri and Peter Behan proposed that myalgic encephalomyelitis/chronic fatigue syndrome was an acquired neurological channelopathy illness, meaning that the symptoms are the result of ion channel transportation problems affecting the body's nervous system. The channelopathy hypothosis was first published in 1999.
Theory[edit | edit source]
Evidence[edit | edit source]
Ion transportation symptoms are recognized in the diagnostic criteria of the International Consensus Criteria.
Notable studies[edit | edit source]
- 1999, Chronic fatigue syndrome is an acquired neurological channelopathy[1]
- 2000, The symptoms of chronic fatigue syndrome are related to abnormal ion channel function[2]
- 2003, Monitoring a Hypothetical Channelopathy in Chronic Fatigue Syndrome: Preliminary Observations[3]
Treatment[edit | edit source]
See also[edit | edit source]
Learn more[edit | edit source]
References[edit | edit source]
- ↑ Chaudhuri, Abhijit; Behan, Peter O. (January 1, 1999). "Chronic fatigue syndrome is an acquired neurological channelopathy". Human Psychopharmacology: Clinical and Experimental. 14 (1). doi:10.1002/(sici)1099-1077(199901)14:1. ISSN 1099-1077.
- ↑ Chaudhuri, A.; Watson, W.S.; Pearn, J.; Behan, P.O. (January 2000). "The symptoms of chronic fatigue syndrome are related to abnormal ion channel function" (PDF). Medical Hypotheses. 54 (1): 59–63. doi:10.1054/mehy.1998.0822. ISSN 0306-9877.
- ↑ Nijs, Jo; De Becker, Pascale; Demanet, Christian; McGregor, Neil R.; Englebienne, Patrick; Verhas, Michel; De Meirleir, Kenny (January 2003). "Monitoring a Hypothetical Channelopathy in Chronic Fatigue Syndrome" (PDF). Journal of Chronic Fatigue Syndrome. 11 (1): 117–133. doi:10.1300/j092v11n01_03. ISSN 1057-3321.
