Borna disease virus

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

The Borna disease virus (BDV) is in the viral order of Mononegavirales. Borna disease is considered to be a zoonotic disease, that is, a disease that spreads from animals to humans. Borna disease virus can be transmitted by many animals including birds, rodents, and horses.[1]

Notable studies[edit | edit source]

  • 1996, Demonstration of Borna disease virus RNA in peripheral blood mononuclear cells derived from Japanese patients with chronic fatigue syndrome.[2] Blood samples from two families, whose members had almost all been diagnosed with CFS, were tested for BDV antibodies. The antibody tests were positive in the family members with CFS, while the healthy members tested negative. (Abstract)
  • 1996, Possible correlation between Borna disease virus infection and Japanese patients with chronic fatigue syndrome.[3] BDV RNA was found in the blood cells of a significant number of CFS patients in the study.
  • 1997, Demonstration on Borna disease virus in patients with chronic fatigue syndrome.[4]
  • 1999, Borna Disease Virus Proteins in Patients with CFS[5]
  • 1999, Absence of evidence of Borna disease virus infection in Swedish patients with Chronic Fatigue Syndrome.[6]
  • 1999, Borna disease virus infection in two family clusters of patients with chronic fatigue syndrome.[7]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. Borna Disease - CDC - Emerging Infectious Diseases
  2. Nakaya, T.; Takahashi, H.; Nakamur, Y.; Kuratsune, H.; Kitani, T.; Machii, T.; Yamanishi, K.; Ikuta, K. (1999). "Borna disease virus infection in two family clusters of patients with chronic fatigue syndrome". Microbiology and Immunology. 43 (7): 679–689. ISSN 0385-5600. PMID 10529109.
  3. Kitani, T.; Kuratsune, H.; Fuke, I.; Nakamura, Y.; Nakaya, T.; Asahi, S.; Tobiume, M.; Yamaguti, K.; Machii, T. (1996). "Possible correlation between Borna disease virus infection and Japanese patients with chronic fatigue syndrome". Microbiology and Immunology. 40 (6): 459–462. ISSN 0385-5600. PMID 8839433.
  4. Nakaya, T.; Kuratsune, H.; Kitani, T.; Ikuta, K. (November 1997). "[Demonstration on Borna disease virus in patients with chronic fatigue syndrome]". Nihon Rinsho. Japanese Journal of Clinical Medicine. 55 (11): 3064–3071. ISSN 0047-1852. PMID 9396313.
  5. Susan Levine. (1999). Borna Disease Virus Proteins in Patients with CFS. Journal of Chronic Fatigue Syndrome, Vol. 5, Iss. 3-4, pp. 199-206. http://dx.doi.org/10.1300/J092v05n03_17
  6. Evengård, B.; Briese, T.; Lindh, G.; Lee, S.; Lipkin, W.I. (October 1999). "Absence of evidence of Borna disease virus infection in Swedish patients with Chronic Fatigue Syndrome". Journal of Neurovirology. 5 (5): 495–499. ISSN 1355-0284. PMID 10568886.
  7. Nakaya, T.; Takahashi, H.; Nakamur, Y.; Kuratsune, H.; Kitani, T.; Machii, T.; Yamanishi, K.; Ikuta, K. (1999). "Borna disease virus infection in two family clusters of patients with chronic fatigue syndrome". Microbiology and Immunology. 43 (7): 679–689. ISSN 0385-5600. PMID 10529109.