Lactate dehydrogenase

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Lactate dehydrogenase (LDH) converts lactic acid to pyruvate and back.

Increased serum concentrations of LDH have been found in ME patients during the acute phase.[1]

Abnormally high LDH was found in patients of the 1955 Royal Free Hospital outbreak.[2]

One study on 579 CDC-criteria CFS patients found lower levels of LDH relative to controls.[3]

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References[edit | edit source]

  1. Fegan, KG; Behan, PO; Bell, EJ (June 1983), "Myalgic encephalomyelitis--report of an epidemic.", J R Coll Gen Pract, 33 (251): 335–337, PMID 6310104
  2. Ramsay, A. Melvin (November 1978). "'Epidemic neuromyasthenia' 1955-1978". Postgraduate Medical Journal. 54: 718–721.
  3. Bates, David W.; Buchwald, Dedra; Lee, Joshua; Kith, Phalla; Doolittle, Teresa; Rutherford, Cynthia; Churchill, W. Hallowell; Schur, Peter H.; Wener, Mark; Wybenga, Donald; Winkelman, James (January 9, 1995). "Clinical Laboratory Test Findings in Patients With Chronic Fatigue Syndrome". Archives of Internal Medicine. 155 (1): 97–103. doi:10.1001/archinte.1995.00430010105014. ISSN 0003-9926.