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Hydrocortisone is the name for the hormone cortisol when supplied as a medication.

Clinical trials in ME/CFS[edit | edit source]

A 1998 double-blind, randomized, placebo-controlled trial found that low dose hydrocortisone led to significant improvement in subjective scores but concluded that the resulting degree of adrenal suppression precludes its practical use.[1]

In 1999, the Institute of Psychiatry, London, did a randomized crossover trial, in which Simon Wessely was an author, where low dose hydrocortisone treatments given to patients with chronic fatigue syndrome were found to reduce fatigue scores and that 28% of patients in the treatment group had reductions in scores that brought them to or close to normal in the short term.[2]

A 2003 double-blind, randomized, placebo-controlled trial in combination with fludrocortisone, a mineralocorticoid, found no difference in self-reported outcomes.[3]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

double blinded trial A clinical trial is double blinded if neither the participants nor the researchers know which treatment group they are allocated to until after the results are interpreted. This reduces bias. (Learn more: www.nottingham.ac.uk)

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.